A Rare Case of the Small Cell Neuroendocrine Carcinoma of urinary Bladder (Anis Hussain Jafri,Aziz Abdullah, Saba Jamal)
Small cell neuroendocrine carcinoma of urinary bladder (SCCB) is a rare, prevalent in males, highly aggressive carcinoma being diagnosed usually at advanced stages. The origin of the disease is unknown; however the multipotent stem cell theory applies best to this case. Histology and immune histoch...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Bahria Univerisy Health Sciences, Campus Karachi
2013-12-01
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| Series: | Journal of Bahria University Medical and Dental College |
| Subjects: | |
| Online Access: | https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/65 |
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| Summary: | Small cell neuroendocrine carcinoma of urinary bladder (SCCB) is a rare, prevalent in males, highly aggressive
carcinoma being diagnosed usually at advanced stages. The origin of the disease is unknown; however the
multipotent stem cell theory applies best to this case. Histology and immune histochemistry shows a tumor which is
indistinguishable from small cell lung carcinoma (SCLC). We report a case of SCCB in a 70 year old female who
presented with history of recurrent urinary tract infections and hematuria for six months. CT scan showed a large
mass in bladder, infiltrating muscle along the left lateral wall with no extra-vesical extension. Cystoscopy revealed a
muscle invasive mass protruding into the bladder lumen, extending from 3-5 o’clock. Initial histopathology showed
poorly differentiated urothelial neoplasm. She underwent an uneventful radical cystectomy with urinary
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| ISSN: | 2220-7562 2617-9482 |