Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat.

Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat.

Circadian clocks, present in almost all cells of the body, are entrained to rhythmic changes in the environment (e.g. light/dark cycles). Genes responsible for this timekeeping are named core-clock genes, which through transcriptional feedback interactions mediated by transcription factor binding to...

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Bibliographic Details
Main Authors: Panteleimon D Mavroudis, Debra C DuBois, Richard R Almon, William J Jusko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0197534/1/pone.0197534.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210220%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210220T173237Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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