Recent Advances in the Treatment of Coronary In-Stent Restenosis
In-stent restenosis (ISR) remains the predominant cause of stent failure and the most common indication for repeat revascularization. Despite technological advances in stent design, ISR continues to pose significant challenges, contributing to increased morbidity and mortality among patients undergo...
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| Format: | Article |
| Language: | English |
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IMR Press
2024-12-01
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| Series: | Reviews in Cardiovascular Medicine |
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| Online Access: | https://www.imrpress.com/journal/RCM/25/12/10.31083/j.rcm2512433 |
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| author | Luca Sartore Mauro Gitto Angelo Oliva Ryota Kakizaki Roxana Mehran Lorenz Räber Alessandro Spirito |
| author_facet | Luca Sartore Mauro Gitto Angelo Oliva Ryota Kakizaki Roxana Mehran Lorenz Räber Alessandro Spirito |
| author_sort | Luca Sartore |
| collection | DOAJ |
| description | In-stent restenosis (ISR) remains the predominant cause of stent failure and the most common indication for repeat revascularization. Despite technological advances in stent design, ISR continues to pose significant challenges, contributing to increased morbidity and mortality among patients undergoing percutaneous coronary interventions. In the last decade, intravascular imaging has emerged as an important method for identifying the mechanisms behind ISR and guiding its treatment. Treatment options for ISR have expanded to include balloon angioplasty, cutting or scoring balloons, intravascular lithotripsy, atheroablative devices, drug-eluting stents, drug-coated balloons, surgical revascularization, and intravascular brachytherapy. The aim of the current review is to describe the classification and mechanisms of ISR, provide a comprehensive and updated overview of the evidence supporting different treatment strategies, suggest a management algorithm, and present insights into future developments in the field. |
| format | Article |
| id | doaj-art-a03c47603b154b6a953eb9b50f4ebee4 |
| institution | DOAJ |
| issn | 1530-6550 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Reviews in Cardiovascular Medicine |
| spelling | doaj-art-a03c47603b154b6a953eb9b50f4ebee42025-08-20T02:39:51ZengIMR PressReviews in Cardiovascular Medicine1530-65502024-12-01251243310.31083/j.rcm2512433S1530-6550(24)01573-4Recent Advances in the Treatment of Coronary In-Stent RestenosisLuca Sartore0Mauro Gitto1Angelo Oliva2Ryota Kakizaki3Roxana Mehran4Lorenz Räber5Alessandro Spirito6Department of Cardiology, Bern University Hospital, Inselspital, CH-3010 Bern, SwitzerlandMount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USAMount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USADepartment of Cardiology, Bern University Hospital, Inselspital, CH-3010 Bern, SwitzerlandMount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USADepartment of Cardiology, Bern University Hospital, Inselspital, CH-3010 Bern, SwitzerlandDepartment of Cardiology, Bern University Hospital, Inselspital, CH-3010 Bern, SwitzerlandIn-stent restenosis (ISR) remains the predominant cause of stent failure and the most common indication for repeat revascularization. Despite technological advances in stent design, ISR continues to pose significant challenges, contributing to increased morbidity and mortality among patients undergoing percutaneous coronary interventions. In the last decade, intravascular imaging has emerged as an important method for identifying the mechanisms behind ISR and guiding its treatment. Treatment options for ISR have expanded to include balloon angioplasty, cutting or scoring balloons, intravascular lithotripsy, atheroablative devices, drug-eluting stents, drug-coated balloons, surgical revascularization, and intravascular brachytherapy. The aim of the current review is to describe the classification and mechanisms of ISR, provide a comprehensive and updated overview of the evidence supporting different treatment strategies, suggest a management algorithm, and present insights into future developments in the field.https://www.imrpress.com/journal/RCM/25/12/10.31083/j.rcm2512433in-stent restenosisdrug eluting stentdrug coated balloonatherectomycutting balloonscoring balloonintravascular lithotripsyintravascular brachytherapyoptical coherence tomographyintravascular ultrasound |
| spellingShingle | Luca Sartore Mauro Gitto Angelo Oliva Ryota Kakizaki Roxana Mehran Lorenz Räber Alessandro Spirito Recent Advances in the Treatment of Coronary In-Stent Restenosis Reviews in Cardiovascular Medicine in-stent restenosis drug eluting stent drug coated balloon atherectomy cutting balloon scoring balloon intravascular lithotripsy intravascular brachytherapy optical coherence tomography intravascular ultrasound |
| title | Recent Advances in the Treatment of Coronary In-Stent Restenosis |
| title_full | Recent Advances in the Treatment of Coronary In-Stent Restenosis |
| title_fullStr | Recent Advances in the Treatment of Coronary In-Stent Restenosis |
| title_full_unstemmed | Recent Advances in the Treatment of Coronary In-Stent Restenosis |
| title_short | Recent Advances in the Treatment of Coronary In-Stent Restenosis |
| title_sort | recent advances in the treatment of coronary in stent restenosis |
| topic | in-stent restenosis drug eluting stent drug coated balloon atherectomy cutting balloon scoring balloon intravascular lithotripsy intravascular brachytherapy optical coherence tomography intravascular ultrasound |
| url | https://www.imrpress.com/journal/RCM/25/12/10.31083/j.rcm2512433 |
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