Cell‐free epigenomes enhanced fragmentomics‐based model for early detection of lung cancer

Cell‐free epigenomes enhanced fragmentomics‐based model for early detection of lung cancer

Abstract Background Lung cancer is a leading cause of cancer mortality, highlighting the need for innovative non‐invasive early detection methods. Although cell‐free DNA (cfDNA) analysis shows promise, its sensitivity in early‐stage lung cancer patients remains a challenge. This study aimed to integ...

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Main Authors: Yadong Wang, Qiang Guo, Zhicheng Huang, Liyang Song, Fei Zhao, Tiantian Gu, Zhe Feng, Haibo Wang, Bowen Li, Daoyun Wang, Bin Zhou, Chao Guo, Yuan Xu, Yang Song, Zhibo Zheng, Zhongxing Bing, Haochen Li, Xiaoqing Yu, Ka Luk Fung, Heqing Xu, Jianhong Shi, Meng Chen, Shuai Hong, Haoxuan Jin, Shiyuan Tong, Sibo Zhu, Chen Zhu, Jinlei Song, Jing Liu, Shanqing Li, Hefei Li, Xueguang Sun, Naixin Liang
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Clinical and Translational Medicine
Subjects:
cell‐free DNA
early cancer screening
epigenomics
liquid biopsy
lung cancer
Online Access:https://doi.org/10.1002/ctm2.70225
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