Bibliometric analysis of pancreatic cancer liver metastasis research: global trends, collaborations, and emerging research hotspots

BackgroundPancreatic cancer liver metastasis (PCLM) is a critical condition characterized by the spread of pancreatic cancer to the liver, significantly contributing to cancer-related mortality. The importance of understanding the epidemiology and research trends in PCLM cannot be overstated, as it...

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Main Authors: Yingjie Huang, Zhijie Yin, Wei Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1546400/full
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author Yingjie Huang
Zhijie Yin
Wei Han
author_facet Yingjie Huang
Zhijie Yin
Wei Han
author_sort Yingjie Huang
collection DOAJ
description BackgroundPancreatic cancer liver metastasis (PCLM) is a critical condition characterized by the spread of pancreatic cancer to the liver, significantly contributing to cancer-related mortality. The importance of understanding the epidemiology and research trends in PCLM cannot be overstated, as it impacts the development of effective treatment strategies and patient care in oncology.MethodThis study provides a comprehensive epidemiological and bibliometric analysis of PCLM research. Advanced visualization tools such as VOSviewer, CiteSpace, and the R package “bibliometrix” were utilized to analyze the literature. A total of 3,941 publications were identified, covering a 15-year period from 2010 to 2024. The methodology included the identification of publication trends, country and institutional contributions, leading journals, and keyword co-occurrence analysis to uncover research hotspots.ResultsThe annual publication counts exhibited an upward trend, peaking at 384 in 2024, indicating a growing interest in PCLM research. The research included contributions from 90 countries and 4386 institutions, with China and the United States being the most prolific. The journal Cancers was identified as the most frequent publisher in this field. Keyword co-occurrence analysis revealed “cancer” and “pancreatic cancer” as key research hotspots, with a focus on prognostic factors and therapeutic strategies. The study also highlighted the importance of international collaboration and identified key contributors in the field.ConclusionThe findings of this study reveal the significant increase in PCLM research output, emphasizing the need for continued investigation and collaboration to improve treatment outcomes and patient care. While the study is limited by its reliance on bibliometric data without experimental validation, it nonetheless provides valuable insights into publication trends and emerging research themes in PCLM. The results underscore the importance of further research to enhance our understanding of this challenging area of oncology and to guide future research directions.
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spelling doaj-art-a02556edc05e45fcbe64481cc118385e2025-08-20T03:12:30ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-07-011510.3389/fonc.2025.15464001546400Bibliometric analysis of pancreatic cancer liver metastasis research: global trends, collaborations, and emerging research hotspotsYingjie HuangZhijie YinWei HanBackgroundPancreatic cancer liver metastasis (PCLM) is a critical condition characterized by the spread of pancreatic cancer to the liver, significantly contributing to cancer-related mortality. The importance of understanding the epidemiology and research trends in PCLM cannot be overstated, as it impacts the development of effective treatment strategies and patient care in oncology.MethodThis study provides a comprehensive epidemiological and bibliometric analysis of PCLM research. Advanced visualization tools such as VOSviewer, CiteSpace, and the R package “bibliometrix” were utilized to analyze the literature. A total of 3,941 publications were identified, covering a 15-year period from 2010 to 2024. The methodology included the identification of publication trends, country and institutional contributions, leading journals, and keyword co-occurrence analysis to uncover research hotspots.ResultsThe annual publication counts exhibited an upward trend, peaking at 384 in 2024, indicating a growing interest in PCLM research. The research included contributions from 90 countries and 4386 institutions, with China and the United States being the most prolific. The journal Cancers was identified as the most frequent publisher in this field. Keyword co-occurrence analysis revealed “cancer” and “pancreatic cancer” as key research hotspots, with a focus on prognostic factors and therapeutic strategies. The study also highlighted the importance of international collaboration and identified key contributors in the field.ConclusionThe findings of this study reveal the significant increase in PCLM research output, emphasizing the need for continued investigation and collaboration to improve treatment outcomes and patient care. While the study is limited by its reliance on bibliometric data without experimental validation, it nonetheless provides valuable insights into publication trends and emerging research themes in PCLM. The results underscore the importance of further research to enhance our understanding of this challenging area of oncology and to guide future research directions.https://www.frontiersin.org/articles/10.3389/fonc.2025.1546400/fullpancreatic cancerliver metastasisbibliometric analysis (BA)global progressresearch trends
spellingShingle Yingjie Huang
Zhijie Yin
Wei Han
Bibliometric analysis of pancreatic cancer liver metastasis research: global trends, collaborations, and emerging research hotspots
Frontiers in Oncology
pancreatic cancer
liver metastasis
bibliometric analysis (BA)
global progress
research trends
title Bibliometric analysis of pancreatic cancer liver metastasis research: global trends, collaborations, and emerging research hotspots
title_full Bibliometric analysis of pancreatic cancer liver metastasis research: global trends, collaborations, and emerging research hotspots
title_fullStr Bibliometric analysis of pancreatic cancer liver metastasis research: global trends, collaborations, and emerging research hotspots
title_full_unstemmed Bibliometric analysis of pancreatic cancer liver metastasis research: global trends, collaborations, and emerging research hotspots
title_short Bibliometric analysis of pancreatic cancer liver metastasis research: global trends, collaborations, and emerging research hotspots
title_sort bibliometric analysis of pancreatic cancer liver metastasis research global trends collaborations and emerging research hotspots
topic pancreatic cancer
liver metastasis
bibliometric analysis (BA)
global progress
research trends
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1546400/full
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AT zhijieyin bibliometricanalysisofpancreaticcancerlivermetastasisresearchglobaltrendscollaborationsandemergingresearchhotspots
AT weihan bibliometricanalysisofpancreaticcancerlivermetastasisresearchglobaltrendscollaborationsandemergingresearchhotspots