Influence of masticatory function on food preferences and cognitive performance in centenarians: an observational study

Abstract Introduction Demographic projections forecast that centenarians’ population growth will continue. “CaT: Centenari a Trieste” is an ongoing study featuring the collection of demographic and anamnestic data, including the analysis of oral variables. Aims evaluate of the possible influence of...

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Main Authors: Katia Rupel, Matteo Biasotto, Filomena Vella, Giulia Ottaviani, Roberto Di Lenarda, Mauro Tettamanti, Gabriella Marcon
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:BDJ Open
Online Access:https://doi.org/10.1038/s41405-025-00321-z
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author Katia Rupel
Matteo Biasotto
Filomena Vella
Giulia Ottaviani
Roberto Di Lenarda
Mauro Tettamanti
Gabriella Marcon
author_facet Katia Rupel
Matteo Biasotto
Filomena Vella
Giulia Ottaviani
Roberto Di Lenarda
Mauro Tettamanti
Gabriella Marcon
author_sort Katia Rupel
collection DOAJ
description Abstract Introduction Demographic projections forecast that centenarians’ population growth will continue. “CaT: Centenari a Trieste” is an ongoing study featuring the collection of demographic and anamnestic data, including the analysis of oral variables. Aims evaluate of the possible influence of past food preferences, taste perception and masticatory function on current cognitive status in a cohort of centenarians. Design Observational transversal study. Materials and Methods 31 participants with mean age 102 ± 2 performed an examination of the oral cavity including the measurement of DMFT (Decayed Missing Filled Teeth), FTUs (functional teeth units), FOUs (functional occlusal units) and 6-n-propylthiouracil (PROP) taste perception assay. Results were correlated with dementia, subjective perception of oral health and food preferences. Results Masticatory function did not correlate with dementia but had a significant impact on oral health perception. When analyzing variables affecting food preferences, PROP taste perception profile and DMFT resulted significantly correlated. Early edentulism didn’t show to affect past dietary preferences. Conclusions our data suggest that in centenarians masticatory function doesn’t seem to correlate to cognitive function, but influences the self-perception of oral health. Such results are an interesting addition to knowledge on the topic as they refer to a population which has never been considered before.
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spelling doaj-art-a01d9c4f437642cdb7770ada42474a8d2025-08-20T03:40:50ZengNature Publishing GroupBDJ Open2056-807X2025-03-011111710.1038/s41405-025-00321-zInfluence of masticatory function on food preferences and cognitive performance in centenarians: an observational studyKatia Rupel0Matteo Biasotto1Filomena Vella2Giulia Ottaviani3Roberto Di Lenarda4Mauro Tettamanti5Gabriella Marcon6Department of Medicine, Surgery and Health Sciences, University of TriesteAzienda Sanitaria Friuli Occidentale (ASFO)Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI)Department of Medicine, Surgery and Health Sciences, University of TriesteDepartment of Medicine, Surgery and Health Sciences, University of TriesteIstituto di Ricerche Farmacologiche Mario Negri IRCCSDepartment of Medicine, Surgery and Health Sciences, University of TriesteAbstract Introduction Demographic projections forecast that centenarians’ population growth will continue. “CaT: Centenari a Trieste” is an ongoing study featuring the collection of demographic and anamnestic data, including the analysis of oral variables. Aims evaluate of the possible influence of past food preferences, taste perception and masticatory function on current cognitive status in a cohort of centenarians. Design Observational transversal study. Materials and Methods 31 participants with mean age 102 ± 2 performed an examination of the oral cavity including the measurement of DMFT (Decayed Missing Filled Teeth), FTUs (functional teeth units), FOUs (functional occlusal units) and 6-n-propylthiouracil (PROP) taste perception assay. Results were correlated with dementia, subjective perception of oral health and food preferences. Results Masticatory function did not correlate with dementia but had a significant impact on oral health perception. When analyzing variables affecting food preferences, PROP taste perception profile and DMFT resulted significantly correlated. Early edentulism didn’t show to affect past dietary preferences. Conclusions our data suggest that in centenarians masticatory function doesn’t seem to correlate to cognitive function, but influences the self-perception of oral health. Such results are an interesting addition to knowledge on the topic as they refer to a population which has never been considered before.https://doi.org/10.1038/s41405-025-00321-z
spellingShingle Katia Rupel
Matteo Biasotto
Filomena Vella
Giulia Ottaviani
Roberto Di Lenarda
Mauro Tettamanti
Gabriella Marcon
Influence of masticatory function on food preferences and cognitive performance in centenarians: an observational study
BDJ Open
title Influence of masticatory function on food preferences and cognitive performance in centenarians: an observational study
title_full Influence of masticatory function on food preferences and cognitive performance in centenarians: an observational study
title_fullStr Influence of masticatory function on food preferences and cognitive performance in centenarians: an observational study
title_full_unstemmed Influence of masticatory function on food preferences and cognitive performance in centenarians: an observational study
title_short Influence of masticatory function on food preferences and cognitive performance in centenarians: an observational study
title_sort influence of masticatory function on food preferences and cognitive performance in centenarians an observational study
url https://doi.org/10.1038/s41405-025-00321-z
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