Intermittent hypoxia aggravates asthma inflammation via NLRP3/IL-1β-dependent pyroptosis mediated by HIF-1α signalling pathway

Intermittent hypoxia aggravates asthma inflammation via NLRP3/IL-1β-dependent pyroptosis mediated by HIF-1α signalling pathway

Abstract. Background:. Asthma is a common chronic inflammatory airway disease and intermittent hypoxia is increasingly recognized as a factor that may impact disease progression. The present study investigated whether intermittent hypoxia (IH) could aggravate asthma by promoting hypoxia-inducible f...

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Main Authors: Ling Zhou, Huojun Zhang, Lu Liu, Fengqin Zhang, Lingling Wang, Pengdou Zheng, Zhenyu Mao, Xiaoyan Zhu, Guisha Zi, Lixiang Chen, Xiaojing Cai, Huiguo Liu, Wei Liu, Peifang Wei
Format: Article
Language:English
Published: Wolters Kluwer 2025-07-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000003608
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