No Relation between Psoriasis and Renal Abnormalities: A Case-Control Study
Multiple observational studies have demonstrated that psoriasis is associated with nephropathy; however, the renal involvement in psoriasis remains largely a matter of debate. The current study was designed to investigate if psoriatic patients are at increased risk of renal abnormalities, in absence...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2018/5301631 |
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| author | Zohreh Tehranchinia Esmat Ghanei Nahid Mohammadi Masoud Partovi-Kia Hoda Rahimi Nikoo Mozafari |
| author_facet | Zohreh Tehranchinia Esmat Ghanei Nahid Mohammadi Masoud Partovi-Kia Hoda Rahimi Nikoo Mozafari |
| author_sort | Zohreh Tehranchinia |
| collection | DOAJ |
| description | Multiple observational studies have demonstrated that psoriasis is associated with nephropathy; however, the renal involvement in psoriasis remains largely a matter of debate. The current study was designed to investigate if psoriatic patients are at increased risk of renal abnormalities, in absence of any other comorbidities. Forty patients (11 women, 29 men, mean age 44.9 ± 15.45 years) with moderate to severe chronic plaque type psoriasis who were not under systemic therapy and 40 age- and gender-matched control subjects were enrolled in the study. Patients and controls with history of diabetes, hypertension, and chronic renal disease were excluded. Urinalysis by dipstick and microscopic evaluation and 24 h proteinuria and albuminuria were measured in all patients and controls. Patients with psoriasis and controls were not significantly different with respect to the prevalence of abnormal urinalysis (7.5% versus 5%, P = 1.0), mean 24 h proteinuria (70.40 ± 24.38 mg/24 h versus 89.40 ± 26.78 mg/24 h, P = 0.30), and albuminuria (14.15 ± 8.12 mg/24 h versus 16.62 ± 8.21 mg/24 h, P = 0.18). The presence of abnormal urinalysis was not more common in patients with psoriasis than in controls. Our study demonstrated that psoriatic patients without any other comorbidities are not at increased risk of kidney disease. |
| format | Article |
| id | doaj-art-a000c3e2bfc5435a897adac3e8bcc170 |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-a000c3e2bfc5435a897adac3e8bcc1702025-08-20T03:38:11ZengWileyThe Scientific World Journal2356-61401537-744X2018-01-01201810.1155/2018/53016315301631No Relation between Psoriasis and Renal Abnormalities: A Case-Control StudyZohreh Tehranchinia0Esmat Ghanei1Nahid Mohammadi2Masoud Partovi-Kia3Hoda Rahimi4Nikoo Mozafari5Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranInternal Medicines Ward, Shahid Beheshti University of Medical Sciences, Tehran, IranSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranMultiple observational studies have demonstrated that psoriasis is associated with nephropathy; however, the renal involvement in psoriasis remains largely a matter of debate. The current study was designed to investigate if psoriatic patients are at increased risk of renal abnormalities, in absence of any other comorbidities. Forty patients (11 women, 29 men, mean age 44.9 ± 15.45 years) with moderate to severe chronic plaque type psoriasis who were not under systemic therapy and 40 age- and gender-matched control subjects were enrolled in the study. Patients and controls with history of diabetes, hypertension, and chronic renal disease were excluded. Urinalysis by dipstick and microscopic evaluation and 24 h proteinuria and albuminuria were measured in all patients and controls. Patients with psoriasis and controls were not significantly different with respect to the prevalence of abnormal urinalysis (7.5% versus 5%, P = 1.0), mean 24 h proteinuria (70.40 ± 24.38 mg/24 h versus 89.40 ± 26.78 mg/24 h, P = 0.30), and albuminuria (14.15 ± 8.12 mg/24 h versus 16.62 ± 8.21 mg/24 h, P = 0.18). The presence of abnormal urinalysis was not more common in patients with psoriasis than in controls. Our study demonstrated that psoriatic patients without any other comorbidities are not at increased risk of kidney disease.http://dx.doi.org/10.1155/2018/5301631 |
| spellingShingle | Zohreh Tehranchinia Esmat Ghanei Nahid Mohammadi Masoud Partovi-Kia Hoda Rahimi Nikoo Mozafari No Relation between Psoriasis and Renal Abnormalities: A Case-Control Study The Scientific World Journal |
| title | No Relation between Psoriasis and Renal Abnormalities: A Case-Control Study |
| title_full | No Relation between Psoriasis and Renal Abnormalities: A Case-Control Study |
| title_fullStr | No Relation between Psoriasis and Renal Abnormalities: A Case-Control Study |
| title_full_unstemmed | No Relation between Psoriasis and Renal Abnormalities: A Case-Control Study |
| title_short | No Relation between Psoriasis and Renal Abnormalities: A Case-Control Study |
| title_sort | no relation between psoriasis and renal abnormalities a case control study |
| url | http://dx.doi.org/10.1155/2018/5301631 |
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