Ursolic Acid Ameliorates Diabetic Nephropathy by Inhibiting JAK2/STAT3-Driven Ferroptosis: Mechanistic Insights from Network Pharmacology and Experimental Validation

Ursolic Acid Ameliorates Diabetic Nephropathy by Inhibiting JAK2/STAT3-Driven Ferroptosis: Mechanistic Insights from Network Pharmacology and Experimental Validation

Yijing Zhou,* Chengli Lou,* Xiuqin Xu, Bo Feng, Xiaoping Fan, Xiangjing Wang Department of Nephropathy, Jiaxing Traditional Chinese Medicine Hospital, Jiaxing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yijing Zhou, Em...

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Bibliographic Details
Main Authors: Zhou Y, Lou C, Xu X, Feng B, Fan X, Wang X
Format: Article
Language:English
Published: Dove Medical Press 2025-08-01
Series:Drug Design, Development and Therapy
Subjects:
Diabetic nephropathy
Ursolic acid
JAK2/STAT3 pathway
Ferroptosis
Network pharmacology
Online Access:https://www.dovepress.com/ursolic-acid-ameliorates-diabetic-nephropathy-by-inhibiting-jak2stat3--peer-reviewed-fulltext-article-DDDT
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