Safety and Visual Outcome of Visian Toric ICL Implantation after Corneal Collagen Cross-Linking in Keratoconus: Up to 2 Years of Follow-Up

Purpose. To evaluate the long-term safety and clinical outcome of phakic Visian toric implantable collamer lens (ICL) insertion after corneal collagen cross-linking (CXL) in progressive keratoconus. Methods. This was a retrospective study of 30 eyes (19 patients), with progressive keratoconus, who u...

Full description

Saved in:
Bibliographic Details
Main Authors: Rafic Antonios, Ali Dirani, Ali Fadlallah, Elias Chelala, Adib Hamade, Carole Cherfane, Elias Jarade
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2015/514834
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849398937963724800
author Rafic Antonios
Ali Dirani
Ali Fadlallah
Elias Chelala
Adib Hamade
Carole Cherfane
Elias Jarade
author_facet Rafic Antonios
Ali Dirani
Ali Fadlallah
Elias Chelala
Adib Hamade
Carole Cherfane
Elias Jarade
author_sort Rafic Antonios
collection DOAJ
description Purpose. To evaluate the long-term safety and clinical outcome of phakic Visian toric implantable collamer lens (ICL) insertion after corneal collagen cross-linking (CXL) in progressive keratoconus. Methods. This was a retrospective study of 30 eyes (19 patients), with progressive keratoconus, who underwent sequential CXL followed by Visian toric ICL implantation after 6 months. Results. At baseline, 6 eyes had stage I, 14 eyes stage II, and 10 eyes stage III keratoconus graded by Amsler-Krumeich classification. At 6 months after CXL, only K (steep) and K (max) decreased significantly from baseline, with no change in visual acuity or refraction. Flattening in keratometric readings was stable thereafter. There was significant improvement in mean uncorrected distance visual acuity (1.57 ± 0.56 to 0.17 ± 0.06 logMAR, P<0.001) and mean corrected distance visual acuity (0.17 ± 0.08 to 0.11 ± 0.05 logMAR, P<0.001) at 12 months after ICL implantation that was maintained at the 2-year follow-up. Mean cylinder power and mean spherical equivalent (SE) also decreased significantly after ICL implantation. A small hyperopic shift in SE (+0.25 D) was observed at 2 years that did not alter visual outcomes. Conclusions. Visian toric ICL implantation following CXL is an effective option for improving visual acuity in patients with keratoconus up to 2 years.
format Article
id doaj-art-9ffcf67733cc470ea5a7d72cef48f03e
institution Kabale University
issn 2090-004X
2090-0058
language English
publishDate 2015-01-01
publisher Wiley
record_format Article
series Journal of Ophthalmology
spelling doaj-art-9ffcf67733cc470ea5a7d72cef48f03e2025-08-20T03:38:27ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/514834514834Safety and Visual Outcome of Visian Toric ICL Implantation after Corneal Collagen Cross-Linking in Keratoconus: Up to 2 Years of Follow-UpRafic Antonios0Ali Dirani1Ali Fadlallah2Elias Chelala3Adib Hamade4Carole Cherfane5Elias Jarade6Faculty of Medicine, American University of Beirut, Beirut, LebanonBeirut Eye Specialist Hospital, P.O. Box 116-5311, Al-Mathaf Square, Beirut, LebanonBeirut Eye Specialist Hospital, P.O. Box 116-5311, Al-Mathaf Square, Beirut, LebanonFaculty of Medicine Beirut, Saint-Joseph University, Beirut, LebanonBeirut Eye Specialist Hospital, P.O. Box 116-5311, Al-Mathaf Square, Beirut, LebanonBeirut Eye Specialist Hospital, P.O. Box 116-5311, Al-Mathaf Square, Beirut, LebanonBeirut Eye Specialist Hospital, P.O. Box 116-5311, Al-Mathaf Square, Beirut, LebanonPurpose. To evaluate the long-term safety and clinical outcome of phakic Visian toric implantable collamer lens (ICL) insertion after corneal collagen cross-linking (CXL) in progressive keratoconus. Methods. This was a retrospective study of 30 eyes (19 patients), with progressive keratoconus, who underwent sequential CXL followed by Visian toric ICL implantation after 6 months. Results. At baseline, 6 eyes had stage I, 14 eyes stage II, and 10 eyes stage III keratoconus graded by Amsler-Krumeich classification. At 6 months after CXL, only K (steep) and K (max) decreased significantly from baseline, with no change in visual acuity or refraction. Flattening in keratometric readings was stable thereafter. There was significant improvement in mean uncorrected distance visual acuity (1.57 ± 0.56 to 0.17 ± 0.06 logMAR, P<0.001) and mean corrected distance visual acuity (0.17 ± 0.08 to 0.11 ± 0.05 logMAR, P<0.001) at 12 months after ICL implantation that was maintained at the 2-year follow-up. Mean cylinder power and mean spherical equivalent (SE) also decreased significantly after ICL implantation. A small hyperopic shift in SE (+0.25 D) was observed at 2 years that did not alter visual outcomes. Conclusions. Visian toric ICL implantation following CXL is an effective option for improving visual acuity in patients with keratoconus up to 2 years.http://dx.doi.org/10.1155/2015/514834
spellingShingle Rafic Antonios
Ali Dirani
Ali Fadlallah
Elias Chelala
Adib Hamade
Carole Cherfane
Elias Jarade
Safety and Visual Outcome of Visian Toric ICL Implantation after Corneal Collagen Cross-Linking in Keratoconus: Up to 2 Years of Follow-Up
Journal of Ophthalmology
title Safety and Visual Outcome of Visian Toric ICL Implantation after Corneal Collagen Cross-Linking in Keratoconus: Up to 2 Years of Follow-Up
title_full Safety and Visual Outcome of Visian Toric ICL Implantation after Corneal Collagen Cross-Linking in Keratoconus: Up to 2 Years of Follow-Up
title_fullStr Safety and Visual Outcome of Visian Toric ICL Implantation after Corneal Collagen Cross-Linking in Keratoconus: Up to 2 Years of Follow-Up
title_full_unstemmed Safety and Visual Outcome of Visian Toric ICL Implantation after Corneal Collagen Cross-Linking in Keratoconus: Up to 2 Years of Follow-Up
title_short Safety and Visual Outcome of Visian Toric ICL Implantation after Corneal Collagen Cross-Linking in Keratoconus: Up to 2 Years of Follow-Up
title_sort safety and visual outcome of visian toric icl implantation after corneal collagen cross linking in keratoconus up to 2 years of follow up
url http://dx.doi.org/10.1155/2015/514834
work_keys_str_mv AT raficantonios safetyandvisualoutcomeofvisiantoriciclimplantationaftercornealcollagencrosslinkinginkeratoconusupto2yearsoffollowup
AT alidirani safetyandvisualoutcomeofvisiantoriciclimplantationaftercornealcollagencrosslinkinginkeratoconusupto2yearsoffollowup
AT alifadlallah safetyandvisualoutcomeofvisiantoriciclimplantationaftercornealcollagencrosslinkinginkeratoconusupto2yearsoffollowup
AT eliaschelala safetyandvisualoutcomeofvisiantoriciclimplantationaftercornealcollagencrosslinkinginkeratoconusupto2yearsoffollowup
AT adibhamade safetyandvisualoutcomeofvisiantoriciclimplantationaftercornealcollagencrosslinkinginkeratoconusupto2yearsoffollowup
AT carolecherfane safetyandvisualoutcomeofvisiantoriciclimplantationaftercornealcollagencrosslinkinginkeratoconusupto2yearsoffollowup
AT eliasjarade safetyandvisualoutcomeofvisiantoriciclimplantationaftercornealcollagencrosslinkinginkeratoconusupto2yearsoffollowup