Technologies to improve sperm retrieval in men undergoing micro-TESE for NOA
Nonobstructive azoospermia (NOA) is considered the most challenging clinical scenario for infertile men and current treatments leave many men unsuccessful at being able to achieve a pregnancy with their partner using their own sperm. Microdissection testicular sperm extraction (micro-TESE) is the ch...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-05-01
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| Series: | Asian Journal of Andrology |
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| Online Access: | https://journals.lww.com/10.4103/aja202450 |
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| _version_ | 1850236349008838656 |
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| author | Parviz K Kavoussi Widi Atmoko Germar-Michael Pinggera |
| author_facet | Parviz K Kavoussi Widi Atmoko Germar-Michael Pinggera |
| author_sort | Parviz K Kavoussi |
| collection | DOAJ |
| description | Nonobstructive azoospermia (NOA) is considered the most challenging clinical scenario for infertile men and current treatments leave many men unsuccessful at being able to achieve a pregnancy with their partner using their own sperm. Microdissection testicular sperm extraction (micro-TESE) is the choice for men with NOA desiring to father children with their own gametes. Micro-TESE results in the highest numbers of sperm cells retrieved for use with in vitro fertilization/intracytoplasmic sperm injection. With suboptimal micro-TESE success rates of sperm retrieval and then pregnancy and live birth using the retrieved sperm with in vitro fertilization/intracytoplasmic sperm injection, advances to improve outcomes are necessary. This article comprehensively reviews the technologies investigated to date to improve the outcomes for men undergoing micro-TESE. |
| format | Article |
| id | doaj-art-9ffbd664040d405a8a0f796dbe37e8d5 |
| institution | OA Journals |
| issn | 1008-682X 1745-7262 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Andrology |
| spelling | doaj-art-9ffbd664040d405a8a0f796dbe37e8d52025-08-20T02:01:58ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622025-05-0127337538210.4103/aja202450Technologies to improve sperm retrieval in men undergoing micro-TESE for NOAParviz K KavoussiWidi AtmokoGermar-Michael PinggeraNonobstructive azoospermia (NOA) is considered the most challenging clinical scenario for infertile men and current treatments leave many men unsuccessful at being able to achieve a pregnancy with their partner using their own sperm. Microdissection testicular sperm extraction (micro-TESE) is the choice for men with NOA desiring to father children with their own gametes. Micro-TESE results in the highest numbers of sperm cells retrieved for use with in vitro fertilization/intracytoplasmic sperm injection. With suboptimal micro-TESE success rates of sperm retrieval and then pregnancy and live birth using the retrieved sperm with in vitro fertilization/intracytoplasmic sperm injection, advances to improve outcomes are necessary. This article comprehensively reviews the technologies investigated to date to improve the outcomes for men undergoing micro-TESE.https://journals.lww.com/10.4103/aja202450intracytoplasmic sperm injectionmicrodissection testicular sperm extractionnonobstructive azoospermia |
| spellingShingle | Parviz K Kavoussi Widi Atmoko Germar-Michael Pinggera Technologies to improve sperm retrieval in men undergoing micro-TESE for NOA Asian Journal of Andrology intracytoplasmic sperm injection microdissection testicular sperm extraction nonobstructive azoospermia |
| title | Technologies to improve sperm retrieval in men undergoing micro-TESE for NOA |
| title_full | Technologies to improve sperm retrieval in men undergoing micro-TESE for NOA |
| title_fullStr | Technologies to improve sperm retrieval in men undergoing micro-TESE for NOA |
| title_full_unstemmed | Technologies to improve sperm retrieval in men undergoing micro-TESE for NOA |
| title_short | Technologies to improve sperm retrieval in men undergoing micro-TESE for NOA |
| title_sort | technologies to improve sperm retrieval in men undergoing micro tese for noa |
| topic | intracytoplasmic sperm injection microdissection testicular sperm extraction nonobstructive azoospermia |
| url | https://journals.lww.com/10.4103/aja202450 |
| work_keys_str_mv | AT parvizkkavoussi technologiestoimprovespermretrievalinmenundergoingmicrotesefornoa AT widiatmoko technologiestoimprovespermretrievalinmenundergoingmicrotesefornoa AT germarmichaelpinggera technologiestoimprovespermretrievalinmenundergoingmicrotesefornoa |