Association of oral manifestations with severity of the disease in ulcerative colitis patients
Abstract Objective Inflammatory bowel diseases (IBD), such as Crohn’s disease (CD) and ulcerative colitis (UC), are chronic conditions primarily affecting the intestines. This study aims to identify the nature and frequency of oral symptoms and signs in patients with ulcerative colitis and to explor...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-10-01
|
| Series: | BMC Gastroenterology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12876-024-03472-9 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850204003156099072 |
|---|---|
| author | Nikta Taghizadeh Tabarsi Nazanin Mortazavi Alireza Norouzi Sima Besharat Nasser Behnampour Negar Asgari |
| author_facet | Nikta Taghizadeh Tabarsi Nazanin Mortazavi Alireza Norouzi Sima Besharat Nasser Behnampour Negar Asgari |
| author_sort | Nikta Taghizadeh Tabarsi |
| collection | DOAJ |
| description | Abstract Objective Inflammatory bowel diseases (IBD), such as Crohn’s disease (CD) and ulcerative colitis (UC), are chronic conditions primarily affecting the intestines. This study aims to identify the nature and frequency of oral symptoms and signs in patients with ulcerative colitis and to explore the connection between these complications and the activity of the disease. Methods This descriptive-analytical study involved ulcerative colitis patients who visited the gastroenterology clinic at Shahid Sayad Shirazi Hospital in Gorgan, along with an equal number of healthy companions as a control group in 2019. A gastroenterology internist assessed the disease severity through clinical examination and a simple clinical disease activity index for colitis patients. The collected data were then analyzed statistically using SPSS version 19. Results The average age of patients in the case group was 41.84 ± 11.66 years, while in the control group it was 40.43 ± 12.67 years. There was a significant correlation between difficulty swallowing, burning sensation in the mouth, vomiting, acidic taste, the presence of oral ulcers, and a coated tongue with the severity of disease activity (p < 0.05). However, no significant relationship was found between other variables and the severity of disease activity (p > 0.05). Conclusion The results of this study confirm that as the severity of ulcerative colitis increases, the occurrence of oral lesions also rises, particularly during severe disease activity. Among oral symptoms, dry mouth had the highest incidence, followed by bad breath and changes in taste. The most common oral lesions observed were a coated tongue, grooved tongue, and oral ulcers, respectively. |
| format | Article |
| id | doaj-art-9ff61e261f2c493fab3e027339a68a90 |
| institution | OA Journals |
| issn | 1471-230X |
| language | English |
| publishDate | 2024-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj-art-9ff61e261f2c493fab3e027339a68a902025-08-20T02:11:22ZengBMCBMC Gastroenterology1471-230X2024-10-012411710.1186/s12876-024-03472-9Association of oral manifestations with severity of the disease in ulcerative colitis patientsNikta Taghizadeh Tabarsi0Nazanin Mortazavi1Alireza Norouzi2Sima Besharat3Nasser Behnampour4Negar Asgari5Dental Research Center, Golestan University of Medical SciencesDental Research Center, Golestan University of Medical SciencesGolestan Research Center of Gastroentrology and Hepatology, Golestan University of Medical SciencesGolestan Research Center of Gastroentrology and Hepatology, Golestan University of Medical SciencesHealth Management and Social Development Research Center, Golestan University of Medical SciencesDepartment of Microbiology, School of Medicine, Golestan University of Medical SciencesAbstract Objective Inflammatory bowel diseases (IBD), such as Crohn’s disease (CD) and ulcerative colitis (UC), are chronic conditions primarily affecting the intestines. This study aims to identify the nature and frequency of oral symptoms and signs in patients with ulcerative colitis and to explore the connection between these complications and the activity of the disease. Methods This descriptive-analytical study involved ulcerative colitis patients who visited the gastroenterology clinic at Shahid Sayad Shirazi Hospital in Gorgan, along with an equal number of healthy companions as a control group in 2019. A gastroenterology internist assessed the disease severity through clinical examination and a simple clinical disease activity index for colitis patients. The collected data were then analyzed statistically using SPSS version 19. Results The average age of patients in the case group was 41.84 ± 11.66 years, while in the control group it was 40.43 ± 12.67 years. There was a significant correlation between difficulty swallowing, burning sensation in the mouth, vomiting, acidic taste, the presence of oral ulcers, and a coated tongue with the severity of disease activity (p < 0.05). However, no significant relationship was found between other variables and the severity of disease activity (p > 0.05). Conclusion The results of this study confirm that as the severity of ulcerative colitis increases, the occurrence of oral lesions also rises, particularly during severe disease activity. Among oral symptoms, dry mouth had the highest incidence, followed by bad breath and changes in taste. The most common oral lesions observed were a coated tongue, grooved tongue, and oral ulcers, respectively.https://doi.org/10.1186/s12876-024-03472-9Inflammatory Bowel diseasesColitisUlcerativeOral manifestationsOral UlcerOral health |
| spellingShingle | Nikta Taghizadeh Tabarsi Nazanin Mortazavi Alireza Norouzi Sima Besharat Nasser Behnampour Negar Asgari Association of oral manifestations with severity of the disease in ulcerative colitis patients BMC Gastroenterology Inflammatory Bowel diseases Colitis Ulcerative Oral manifestations Oral Ulcer Oral health |
| title | Association of oral manifestations with severity of the disease in ulcerative colitis patients |
| title_full | Association of oral manifestations with severity of the disease in ulcerative colitis patients |
| title_fullStr | Association of oral manifestations with severity of the disease in ulcerative colitis patients |
| title_full_unstemmed | Association of oral manifestations with severity of the disease in ulcerative colitis patients |
| title_short | Association of oral manifestations with severity of the disease in ulcerative colitis patients |
| title_sort | association of oral manifestations with severity of the disease in ulcerative colitis patients |
| topic | Inflammatory Bowel diseases Colitis Ulcerative Oral manifestations Oral Ulcer Oral health |
| url | https://doi.org/10.1186/s12876-024-03472-9 |
| work_keys_str_mv | AT niktataghizadehtabarsi associationoforalmanifestationswithseverityofthediseaseinulcerativecolitispatients AT nazaninmortazavi associationoforalmanifestationswithseverityofthediseaseinulcerativecolitispatients AT alirezanorouzi associationoforalmanifestationswithseverityofthediseaseinulcerativecolitispatients AT simabesharat associationoforalmanifestationswithseverityofthediseaseinulcerativecolitispatients AT nasserbehnampour associationoforalmanifestationswithseverityofthediseaseinulcerativecolitispatients AT negarasgari associationoforalmanifestationswithseverityofthediseaseinulcerativecolitispatients |