From detection to elimination: iron-based nanomaterials driving tumor imaging and advanced therapies
Iron-based nanomaterials (INMs), due to their particular magnetic property, excellent biocompatibility, and functionality, have been developed into powerful tools in both tumor diagnosis and therapy. We give an overview here on how INMs such as iron oxide nanoparticles, element-doped nanocomposites,...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1536779/full |
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| author | Dong Xie Linglin Sun Manxiang Wu Qiang Li |
| author_facet | Dong Xie Linglin Sun Manxiang Wu Qiang Li |
| author_sort | Dong Xie |
| collection | DOAJ |
| description | Iron-based nanomaterials (INMs), due to their particular magnetic property, excellent biocompatibility, and functionality, have been developed into powerful tools in both tumor diagnosis and therapy. We give an overview here on how INMs such as iron oxide nanoparticles, element-doped nanocomposites, and iron-based organic frameworks (MOFs) display versatility for tumor imaging and therapy improvement. In terms of imaging, INMs improve the sensitivity and accuracy of techniques such as magnetic resonance imaging (MRI) and photoacoustic imaging (PAI) and support the development of multimodal imaging platforms. Regarding treatment, INMs play a key role in advanced strategies such as immunotherapy, magnetic hyperthermia, and synergistic combination therapy, which effectively overcome tumor-induced drug resistance and reduce systemic toxicity. The integration of INMs with artificial intelligence (AI) and radiomics further expands its capabilities for precise tumor identification, and treatment optimization, and amplifies treatment monitoring. INMs now link materials science with advanced computing and clinical innovations to enable next-generation cancer diagnostics and therapeutics. |
| format | Article |
| id | doaj-art-9fefae9b9c6f4e7d8430be0a2729cd39 |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-9fefae9b9c6f4e7d8430be0a2729cd392025-02-07T05:10:36ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-02-011510.3389/fonc.2025.15367791536779From detection to elimination: iron-based nanomaterials driving tumor imaging and advanced therapiesDong Xie0Linglin Sun1Manxiang Wu2Qiang Li3Department of Radiology, The Affiliated People’s Hospital of Ningbo University, Ningbo, ChinaDepartment of Radiology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Radiology, The Affiliated People’s Hospital of Ningbo University, Ningbo, ChinaDepartment of Radiology, The Affiliated People’s Hospital of Ningbo University, Ningbo, ChinaIron-based nanomaterials (INMs), due to their particular magnetic property, excellent biocompatibility, and functionality, have been developed into powerful tools in both tumor diagnosis and therapy. We give an overview here on how INMs such as iron oxide nanoparticles, element-doped nanocomposites, and iron-based organic frameworks (MOFs) display versatility for tumor imaging and therapy improvement. In terms of imaging, INMs improve the sensitivity and accuracy of techniques such as magnetic resonance imaging (MRI) and photoacoustic imaging (PAI) and support the development of multimodal imaging platforms. Regarding treatment, INMs play a key role in advanced strategies such as immunotherapy, magnetic hyperthermia, and synergistic combination therapy, which effectively overcome tumor-induced drug resistance and reduce systemic toxicity. The integration of INMs with artificial intelligence (AI) and radiomics further expands its capabilities for precise tumor identification, and treatment optimization, and amplifies treatment monitoring. INMs now link materials science with advanced computing and clinical innovations to enable next-generation cancer diagnostics and therapeutics.https://www.frontiersin.org/articles/10.3389/fonc.2025.1536779/fulliron-based nanomaterialstumor imagingmagnetic hyperthermiaimmunotherapyartificial intelligence |
| spellingShingle | Dong Xie Linglin Sun Manxiang Wu Qiang Li From detection to elimination: iron-based nanomaterials driving tumor imaging and advanced therapies Frontiers in Oncology iron-based nanomaterials tumor imaging magnetic hyperthermia immunotherapy artificial intelligence |
| title | From detection to elimination: iron-based nanomaterials driving tumor imaging and advanced therapies |
| title_full | From detection to elimination: iron-based nanomaterials driving tumor imaging and advanced therapies |
| title_fullStr | From detection to elimination: iron-based nanomaterials driving tumor imaging and advanced therapies |
| title_full_unstemmed | From detection to elimination: iron-based nanomaterials driving tumor imaging and advanced therapies |
| title_short | From detection to elimination: iron-based nanomaterials driving tumor imaging and advanced therapies |
| title_sort | from detection to elimination iron based nanomaterials driving tumor imaging and advanced therapies |
| topic | iron-based nanomaterials tumor imaging magnetic hyperthermia immunotherapy artificial intelligence |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1536779/full |
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