Targeting NEDD8 in pediatric acute myeloid leukemia: an integrated bioinformatics and experimental approach

Targeting NEDD8 in pediatric acute myeloid leukemia: an integrated bioinformatics and experimental approach

This study systematically explored the role of NEDD8 in pediatric acute myeloid leukemia (AML) through patient sample analysis, database mining, and in vitro experiments. Our results demonstrated that NEDD8 was significantly overexpressed in newly diagnosed pediatric AML patients and was associated...

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Bibliographic Details
Main Authors: Jian Sun, Cui Liu, Guangli Yang, Qian Li, Yang An, Yin Zhu, Pingping Zhang, Yaning Guan, Chang Peng, Zuochen Du, Pei Huang, Yan Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Hematology
Subjects:
Acute myeloid leukemia
pediatric
NEDD8
prognosis
cell cycle
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2025.2478650
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