Methods to address functional unblinding of raters in CNS trials
Abstract Treatment-emergent adverse events (TEAEs) associated with the unique properties of a pharmaceutical product may functionally unblind clinician ratings, obscure true medication effects, and affect confidence about clinical trial results. Central nervous system studies are particularly suscep...
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Main Authors: | Steven D. Targum, William P. Horan, Vicki G. Davis, Alan Breier, Stephen K. Brannan |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2025-02-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-025-03262-1 |
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