Photoperiod-Induced Neuroplasticity in the Circadian System
Seasonal changes in light exposure have profound effects on behavioral and physiological functions in many species, including effects on mood and cognitive function in humans. The mammalian brain’s master circadian clock, the suprachiasmatic nucleus (SCN), transmits information about external light...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2018/5147585 |
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| author | Alessandra Porcu Malini Riddle Davide Dulcis David K. Welsh |
| author_facet | Alessandra Porcu Malini Riddle Davide Dulcis David K. Welsh |
| author_sort | Alessandra Porcu |
| collection | DOAJ |
| description | Seasonal changes in light exposure have profound effects on behavioral and physiological functions in many species, including effects on mood and cognitive function in humans. The mammalian brain’s master circadian clock, the suprachiasmatic nucleus (SCN), transmits information about external light conditions to other brain regions, including some implicated in mood and cognition. Although the detailed mechanisms are not yet known, the SCN undergoes highly plastic changes at the cellular and network levels under different light conditions. We therefore propose that the SCN may be an essential mediator of the effects of seasonal changes of day length on mental health. In this review, we explore various forms of neuroplasticity that occur in the SCN and other brain regions to facilitate seasonal adaptation, particularly altered phase distribution of cellular circadian oscillators in the SCN and changes in hypothalamic neurotransmitter expression. |
| format | Article |
| id | doaj-art-9fc8de7416ae43029ed0e8038ce17f4e |
| institution | OA Journals |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-9fc8de7416ae43029ed0e8038ce17f4e2025-08-20T02:20:51ZengWileyNeural Plasticity2090-59041687-54432018-01-01201810.1155/2018/51475855147585Photoperiod-Induced Neuroplasticity in the Circadian SystemAlessandra Porcu0Malini Riddle1Davide Dulcis2David K. Welsh3Department of Psychiatry and Center for Circadian Biology, University of California, San Diego, 9500 Gilman Dr., San Diego, CA MC-0603, USADepartment of Psychiatry and Center for Circadian Biology, University of California, San Diego, 9500 Gilman Dr., San Diego, CA MC-0603, USADepartment of Psychiatry and Center for Circadian Biology, University of California, San Diego, 9500 Gilman Dr., San Diego, CA MC-0603, USADepartment of Psychiatry and Center for Circadian Biology, University of California, San Diego, 9500 Gilman Dr., San Diego, CA MC-0603, USASeasonal changes in light exposure have profound effects on behavioral and physiological functions in many species, including effects on mood and cognitive function in humans. The mammalian brain’s master circadian clock, the suprachiasmatic nucleus (SCN), transmits information about external light conditions to other brain regions, including some implicated in mood and cognition. Although the detailed mechanisms are not yet known, the SCN undergoes highly plastic changes at the cellular and network levels under different light conditions. We therefore propose that the SCN may be an essential mediator of the effects of seasonal changes of day length on mental health. In this review, we explore various forms of neuroplasticity that occur in the SCN and other brain regions to facilitate seasonal adaptation, particularly altered phase distribution of cellular circadian oscillators in the SCN and changes in hypothalamic neurotransmitter expression.http://dx.doi.org/10.1155/2018/5147585 |
| spellingShingle | Alessandra Porcu Malini Riddle Davide Dulcis David K. Welsh Photoperiod-Induced Neuroplasticity in the Circadian System Neural Plasticity |
| title | Photoperiod-Induced Neuroplasticity in the Circadian System |
| title_full | Photoperiod-Induced Neuroplasticity in the Circadian System |
| title_fullStr | Photoperiod-Induced Neuroplasticity in the Circadian System |
| title_full_unstemmed | Photoperiod-Induced Neuroplasticity in the Circadian System |
| title_short | Photoperiod-Induced Neuroplasticity in the Circadian System |
| title_sort | photoperiod induced neuroplasticity in the circadian system |
| url | http://dx.doi.org/10.1155/2018/5147585 |
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