Dermatomyositis following resection of thyroid and breast cancer: a case report and literature review

BackgroundDermatomyositis is an idiopathic inflammatory myopathy and occurs as a paraneoplastic syndrome. Here, we report an unusual case of dermatomyositis that developed in a patient after the resection of thyroid cancer and breast cancer. The intercorrelation between dermatomyositis and neoplasti...

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Main Authors: Miaomiao Yang, Jiannan Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1474481/full
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author Miaomiao Yang
Jiannan Liu
author_facet Miaomiao Yang
Jiannan Liu
author_sort Miaomiao Yang
collection DOAJ
description BackgroundDermatomyositis is an idiopathic inflammatory myopathy and occurs as a paraneoplastic syndrome. Here, we report an unusual case of dermatomyositis that developed in a patient after the resection of thyroid cancer and breast cancer. The intercorrelation between dermatomyositis and neoplastic disorders was discussed.Case presentationA 60-year-old female farmer was diagnosed with thyroid cancer and breast cancer and then developed dermatomyositis after two curative surgeries and adjuvant chemotherapy. Dermatomyositic symptoms occurred after the fifth cycle of adjuvant chemotherapy for breast cancer and deteriorated progressively. Case history, imaging, and laboratory data were reviewed. This patient subsequently received systemic immunosuppressant therapy and thus dermatomyositis gradually resolved.ConclusionsA combination of thyroid cancer and breast cancer is thought to be very rare, especially in patients who develop dermatomyositis after thyroidectomy and mastectomy. An extraordinary case was reported in this study. Potential mechanisms for the development of dermatomyositis and novel insights neoplastic autoimmune diseases were proposed.
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spelling doaj-art-9fbfe7ac4ef34007b74ab4fe8d5a4a662025-01-21T08:36:51ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011510.3389/fonc.2025.14744811474481Dermatomyositis following resection of thyroid and breast cancer: a case report and literature reviewMiaomiao YangJiannan LiuBackgroundDermatomyositis is an idiopathic inflammatory myopathy and occurs as a paraneoplastic syndrome. Here, we report an unusual case of dermatomyositis that developed in a patient after the resection of thyroid cancer and breast cancer. The intercorrelation between dermatomyositis and neoplastic disorders was discussed.Case presentationA 60-year-old female farmer was diagnosed with thyroid cancer and breast cancer and then developed dermatomyositis after two curative surgeries and adjuvant chemotherapy. Dermatomyositic symptoms occurred after the fifth cycle of adjuvant chemotherapy for breast cancer and deteriorated progressively. Case history, imaging, and laboratory data were reviewed. This patient subsequently received systemic immunosuppressant therapy and thus dermatomyositis gradually resolved.ConclusionsA combination of thyroid cancer and breast cancer is thought to be very rare, especially in patients who develop dermatomyositis after thyroidectomy and mastectomy. An extraordinary case was reported in this study. Potential mechanisms for the development of dermatomyositis and novel insights neoplastic autoimmune diseases were proposed.https://www.frontiersin.org/articles/10.3389/fonc.2025.1474481/fulldermatomyositisthyroid cancerbreast cancerparaneoplastic syndromeautoimmunity
spellingShingle Miaomiao Yang
Jiannan Liu
Dermatomyositis following resection of thyroid and breast cancer: a case report and literature review
Frontiers in Oncology
dermatomyositis
thyroid cancer
breast cancer
paraneoplastic syndrome
autoimmunity
title Dermatomyositis following resection of thyroid and breast cancer: a case report and literature review
title_full Dermatomyositis following resection of thyroid and breast cancer: a case report and literature review
title_fullStr Dermatomyositis following resection of thyroid and breast cancer: a case report and literature review
title_full_unstemmed Dermatomyositis following resection of thyroid and breast cancer: a case report and literature review
title_short Dermatomyositis following resection of thyroid and breast cancer: a case report and literature review
title_sort dermatomyositis following resection of thyroid and breast cancer a case report and literature review
topic dermatomyositis
thyroid cancer
breast cancer
paraneoplastic syndrome
autoimmunity
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1474481/full
work_keys_str_mv AT miaomiaoyang dermatomyositisfollowingresectionofthyroidandbreastcanceracasereportandliteraturereview
AT jiannanliu dermatomyositisfollowingresectionofthyroidandbreastcanceracasereportandliteraturereview