Reversal deterioration of renal function accompanied with primary hypothyrodism

Introduction. Hypothyroidism is often accompanied with decline of kidney function, or inability to maintain electrolyte balance. These changes are usually overlooked in everyday practice. Early recognition of this association eliminates unnecessary diagnostic procedures that postpone the adequat...

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Main Author: Dragović Tamara
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2012-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501202205D.pdf
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author Dragović Tamara
author_facet Dragović Tamara
author_sort Dragović Tamara
collection DOAJ
description Introduction. Hypothyroidism is often accompanied with decline of kidney function, or inability to maintain electrolyte balance. These changes are usually overlooked in everyday practice. Early recognition of this association eliminates unnecessary diagnostic procedures that postpone the adequate treatment. Case report. Two patients with elevated serum creatinine levels due to primary autoimmune hypothyroidism, with complete recovery of creatinine clearance after thyroid hormone substitution therapy are presented. The first patient was a young male whose laboratory tests suggested acute renal failure, and the delicate clinical presentation of reduced thyroid function. The second patient was an elderly woman with a history of a long-term signs and symptoms attributed to ageing, including the deterioration of renal function, with consequently delayed diagnosis of hypothyroidism. Conclusion. Serum thyrotropin and thyroxin levels measurement should be done in all cases of renal failure with undefined renal desease, even if the typical clinical presentation of hypothyroidism is absent. Thyroid hormone assays sholud also be performed in all patients with chronic kidney disease whose kidney function is rapidly worsening.
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spelling doaj-art-9fbd15bf46f04574876b392ba8d811ae2025-08-20T03:38:27ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502012-01-0169220520810.2298/VSP1202205DReversal deterioration of renal function accompanied with primary hypothyrodismDragović TamaraIntroduction. Hypothyroidism is often accompanied with decline of kidney function, or inability to maintain electrolyte balance. These changes are usually overlooked in everyday practice. Early recognition of this association eliminates unnecessary diagnostic procedures that postpone the adequate treatment. Case report. Two patients with elevated serum creatinine levels due to primary autoimmune hypothyroidism, with complete recovery of creatinine clearance after thyroid hormone substitution therapy are presented. The first patient was a young male whose laboratory tests suggested acute renal failure, and the delicate clinical presentation of reduced thyroid function. The second patient was an elderly woman with a history of a long-term signs and symptoms attributed to ageing, including the deterioration of renal function, with consequently delayed diagnosis of hypothyroidism. Conclusion. Serum thyrotropin and thyroxin levels measurement should be done in all cases of renal failure with undefined renal desease, even if the typical clinical presentation of hypothyroidism is absent. Thyroid hormone assays sholud also be performed in all patients with chronic kidney disease whose kidney function is rapidly worsening.http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501202205D.pdfhypothyroidismrenal insufficiencydiagnosisthyrotropinthyroxinetreatment outcome
spellingShingle Dragović Tamara
Reversal deterioration of renal function accompanied with primary hypothyrodism
Vojnosanitetski Pregled
hypothyroidism
renal insufficiency
diagnosis
thyrotropin
thyroxine
treatment outcome
title Reversal deterioration of renal function accompanied with primary hypothyrodism
title_full Reversal deterioration of renal function accompanied with primary hypothyrodism
title_fullStr Reversal deterioration of renal function accompanied with primary hypothyrodism
title_full_unstemmed Reversal deterioration of renal function accompanied with primary hypothyrodism
title_short Reversal deterioration of renal function accompanied with primary hypothyrodism
title_sort reversal deterioration of renal function accompanied with primary hypothyrodism
topic hypothyroidism
renal insufficiency
diagnosis
thyrotropin
thyroxine
treatment outcome
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501202205D.pdf
work_keys_str_mv AT dragovictamara reversaldeteriorationofrenalfunctionaccompaniedwithprimaryhypothyrodism