HELLP syndrome: clinical features and therapeutic orientation
HELLP syndrome is a severe pregnancy complication characterized by hemolysis, elevated liver enzymes, and thrombocytopenia. It affects between 0.2% and 0.9% of pregnancies, usually between 27 and 37 weeks. Although it is associated with pre-eclampsia, it can manifest without its typical signs, compl...
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2025-04-01
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| Series: | Medicina Universitaria |
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| Online Access: | https://www.medicinauniversitaria.org/frame_eng.php?id=273 |
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| author | César H. Gutiérrez-Aguirre David Viznado-Romero |
| author_facet | César H. Gutiérrez-Aguirre David Viznado-Romero |
| author_sort | César H. Gutiérrez-Aguirre |
| collection | DOAJ |
| description | HELLP syndrome is a severe pregnancy complication characterized by hemolysis, elevated liver enzymes, and thrombocytopenia. It affects between 0.2% and 0.9% of pregnancies, usually between 27 and 37 weeks. Although it is associated with pre-eclampsia, it can manifest without its typical signs, complicating the diagnosis. Angiogenic markers, such as the sFlt-1/placental growth factor ratio, have shown utility in the early identification and differentiation of HELLP syndrome. Timely management is crucial to reduce maternal and fetal morbidity and mortality, requiring close surveillance and expert obstetric care.
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| format | Article |
| id | doaj-art-9fb4a5f491ca4a529dfaf15e301534d0 |
| institution | DOAJ |
| issn | 1665-5796 2530-0709 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Permanyer |
| record_format | Article |
| series | Medicina Universitaria |
| spelling | doaj-art-9fb4a5f491ca4a529dfaf15e301534d02025-08-20T03:10:42ZengPermanyerMedicina Universitaria1665-57962530-07092025-04-0127210.24875/RMU.24000049HELLP syndrome: clinical features and therapeutic orientationCésar H. Gutiérrez-Aguirre0David Viznado-Romero1Hematology Service, “Dr. José Eleuterio González” University Hospital, Autonomous University of Nuevo León; Department of Gynecology and Obstetrics, Hospital N.º 23 “Dr. Ignacio Morones Prieto”, IMSS; Monterrey, Nuevo León, MexicoHematology Service, School of Medicine, Autonomous University of Nuevo León, Monterrey, Nuevo León, MexicoHELLP syndrome is a severe pregnancy complication characterized by hemolysis, elevated liver enzymes, and thrombocytopenia. It affects between 0.2% and 0.9% of pregnancies, usually between 27 and 37 weeks. Although it is associated with pre-eclampsia, it can manifest without its typical signs, complicating the diagnosis. Angiogenic markers, such as the sFlt-1/placental growth factor ratio, have shown utility in the early identification and differentiation of HELLP syndrome. Timely management is crucial to reduce maternal and fetal morbidity and mortality, requiring close surveillance and expert obstetric care. https://www.medicinauniversitaria.org/frame_eng.php?id=273HELLP syndrome. Pre-eclampsia. Hemolytic anemia. Thrombocytopenia. |
| spellingShingle | César H. Gutiérrez-Aguirre David Viznado-Romero HELLP syndrome: clinical features and therapeutic orientation Medicina Universitaria HELLP syndrome. Pre-eclampsia. Hemolytic anemia. Thrombocytopenia. |
| title | HELLP syndrome: clinical features and therapeutic orientation |
| title_full | HELLP syndrome: clinical features and therapeutic orientation |
| title_fullStr | HELLP syndrome: clinical features and therapeutic orientation |
| title_full_unstemmed | HELLP syndrome: clinical features and therapeutic orientation |
| title_short | HELLP syndrome: clinical features and therapeutic orientation |
| title_sort | hellp syndrome clinical features and therapeutic orientation |
| topic | HELLP syndrome. Pre-eclampsia. Hemolytic anemia. Thrombocytopenia. |
| url | https://www.medicinauniversitaria.org/frame_eng.php?id=273 |
| work_keys_str_mv | AT cesarhgutierrezaguirre hellpsyndromeclinicalfeaturesandtherapeuticorientation AT davidviznadoromero hellpsyndromeclinicalfeaturesandtherapeuticorientation |