Neuromorphic deviations associated with transcriptomic expression and specific cell type in Alzheimer’s disease

Neuromorphic deviations associated with transcriptomic expression and specific cell type in Alzheimer’s disease

Abstract Alzheimer’s disease (AD) is known to be associated with cortical anatomical atrophy and neurodegeneration across various brain regions. However, the relationships between brain structural changes in AD and gene expression remain unclear. We perform the morphometric similarity network (MSN)...

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Bibliographic Details
Main Authors: Jinzhong Peng, Qin Tang, Yilu Li, Lin Liu, Bharat Bhusan Biswal, Pan Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Alzheimer’s disease
Cognitive decline
Cell types
Morphometric similarity network
Gene expression
Online Access:https://doi.org/10.1038/s41598-025-90872-w
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