Preparation, Characterization, and Antimicrobial Activities of Bimetallic Complexes of Sarcosine with Zn(II) and Sn(IV)

Heterobimetallic complexes of Zn(II) and Sn(IV) with sarcosine have been synthesized at room temperature under stirring conditions by the reaction of sarcosine and zinc acetate in 2 : 1 molar ratio followed by the stepwise addition of CS2 and organotin(IV) halides, where R = Me, n-Bu, and Ph. The co...

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Main Authors: Yasir Arafat, Saqib Ali, Saira Shahzadi, Muhammad Shahid
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2013/351262
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author Yasir Arafat
Saqib Ali
Saira Shahzadi
Muhammad Shahid
author_facet Yasir Arafat
Saqib Ali
Saira Shahzadi
Muhammad Shahid
author_sort Yasir Arafat
collection DOAJ
description Heterobimetallic complexes of Zn(II) and Sn(IV) with sarcosine have been synthesized at room temperature under stirring conditions by the reaction of sarcosine and zinc acetate in 2 : 1 molar ratio followed by the stepwise addition of CS2 and organotin(IV) halides, where R = Me, n-Bu, and Ph. The complexes were characterized by elemental analysis, FT-IR and NMR (1H, 13C) spectroscopy. IR data showed that the ligand acts in a bidentate manner. NMR data revealed the four coordinate geometry in solution state. In vitro antimicrobial activities data showed that complexes (3) and (4) were effective against bacterial and fungal strains with few exceptions.
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spelling doaj-art-9f952e9bf2834d5a8658e2effe8900452025-02-03T05:54:14ZengWileyBioinorganic Chemistry and Applications1565-36331687-479X2013-01-01201310.1155/2013/351262351262Preparation, Characterization, and Antimicrobial Activities of Bimetallic Complexes of Sarcosine with Zn(II) and Sn(IV)Yasir Arafat0Saqib Ali1Saira Shahzadi2Muhammad Shahid3Department of Chemistry, GC University, Faisalabad 38000, PakistanDepartment of Chemistry, Quaid-i-Azam University, Islamabad 45320, PakistanDepartment of Chemistry, GC University, Faisalabad 38000, PakistanDepartment of Chemistry and Biochemistry, University of Agriculture, Faisalabad 38000, PakistanHeterobimetallic complexes of Zn(II) and Sn(IV) with sarcosine have been synthesized at room temperature under stirring conditions by the reaction of sarcosine and zinc acetate in 2 : 1 molar ratio followed by the stepwise addition of CS2 and organotin(IV) halides, where R = Me, n-Bu, and Ph. The complexes were characterized by elemental analysis, FT-IR and NMR (1H, 13C) spectroscopy. IR data showed that the ligand acts in a bidentate manner. NMR data revealed the four coordinate geometry in solution state. In vitro antimicrobial activities data showed that complexes (3) and (4) were effective against bacterial and fungal strains with few exceptions.http://dx.doi.org/10.1155/2013/351262
spellingShingle Yasir Arafat
Saqib Ali
Saira Shahzadi
Muhammad Shahid
Preparation, Characterization, and Antimicrobial Activities of Bimetallic Complexes of Sarcosine with Zn(II) and Sn(IV)
Bioinorganic Chemistry and Applications
title Preparation, Characterization, and Antimicrobial Activities of Bimetallic Complexes of Sarcosine with Zn(II) and Sn(IV)
title_full Preparation, Characterization, and Antimicrobial Activities of Bimetallic Complexes of Sarcosine with Zn(II) and Sn(IV)
title_fullStr Preparation, Characterization, and Antimicrobial Activities of Bimetallic Complexes of Sarcosine with Zn(II) and Sn(IV)
title_full_unstemmed Preparation, Characterization, and Antimicrobial Activities of Bimetallic Complexes of Sarcosine with Zn(II) and Sn(IV)
title_short Preparation, Characterization, and Antimicrobial Activities of Bimetallic Complexes of Sarcosine with Zn(II) and Sn(IV)
title_sort preparation characterization and antimicrobial activities of bimetallic complexes of sarcosine with zn ii and sn iv
url http://dx.doi.org/10.1155/2013/351262
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