Myocarditis associated with Salmonella enterica serovar Weltevreden gastroenteritis in medical practitioner; case report from South India
Salmonella enterica serovar Weltevreden, a non-typhoidal serovar, has emerged as a significant foodborne pathogen, particularly in Southeast Asian countries. While it is commonly associated with gastroenteritis and foodborne outbreaks, it can also lead to invasive infections in immunocompromised adu...
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Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1513974/full |
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| author | Mahadevaiah Neelambike Sumana Morubagal Raghavendra Rao Vidyavathi B. Chitharagi Badveti Satyasai Supreeta R. Shettar Veerabhadra G. S. Swamy Chinchana S. Eshwarappa Yogeesh D. Maheshwarappa |
| author_facet | Mahadevaiah Neelambike Sumana Morubagal Raghavendra Rao Vidyavathi B. Chitharagi Badveti Satyasai Supreeta R. Shettar Veerabhadra G. S. Swamy Chinchana S. Eshwarappa Yogeesh D. Maheshwarappa |
| author_sort | Mahadevaiah Neelambike Sumana |
| collection | DOAJ |
| description | Salmonella enterica serovar Weltevreden, a non-typhoidal serovar, has emerged as a significant foodborne pathogen, particularly in Southeast Asian countries. While it is commonly associated with gastroenteritis and foodborne outbreaks, it can also lead to invasive infections in immunocompromised adults and neonates. This case report presents a rare instance of myocarditis associated with Salmonella Weltevreden gastroenteritis in a 43-year-old healthy male physician from South India. The patient had a month-long history of intermittent fever, which worsened 2 days before admission, along with myalgia and headache. A day after the admission the patient developed diarrhea. Upon investigation, stool culture revealed Salmonella enterica serovar Weltevreden. Notably, the patient had a genetic predisposition to inflammatory bowel disease and reported recent use of nonsteroidal anti-inflammatory drugs, which may have increased his susceptibility to non-typhoidal Salmonella infection. The patient also developed myocarditis, making this the first reported case of Weltevreden-associated myocarditis in the region. Antimicrobial susceptibility testing indicated ciprofloxacin susceptibility, an increasingly rare finding, as most reported serovar Weltevreden cases exhibit ciprofloxacin resistance. The patient recovered following treatment with ciprofloxacin and was discharged with instructions for follow-up. This case highlights the need for heightened awareness of the potential for non-typhoidal Salmonella infections to cause systemic manifestations, even in individuals without major underlying comorbidities. Continuous monitoring of antimicrobial resistance patterns and strict food safety measures are essential to control outbreaks of these emerging pathogens. |
| format | Article |
| id | doaj-art-9f8f73f8d99c4bfcb61e93267d3ffb90 |
| institution | DOAJ |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-9f8f73f8d99c4bfcb61e93267d3ffb902025-08-20T03:00:08ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-03-011210.3389/fmed.2025.15139741513974Myocarditis associated with Salmonella enterica serovar Weltevreden gastroenteritis in medical practitioner; case report from South IndiaMahadevaiah Neelambike SumanaMorubagal Raghavendra RaoVidyavathi B. ChitharagiBadveti SatyasaiSupreeta R. ShettarVeerabhadra G. S. SwamyChinchana S. EshwarappaYogeesh D. MaheshwarappaSalmonella enterica serovar Weltevreden, a non-typhoidal serovar, has emerged as a significant foodborne pathogen, particularly in Southeast Asian countries. While it is commonly associated with gastroenteritis and foodborne outbreaks, it can also lead to invasive infections in immunocompromised adults and neonates. This case report presents a rare instance of myocarditis associated with Salmonella Weltevreden gastroenteritis in a 43-year-old healthy male physician from South India. The patient had a month-long history of intermittent fever, which worsened 2 days before admission, along with myalgia and headache. A day after the admission the patient developed diarrhea. Upon investigation, stool culture revealed Salmonella enterica serovar Weltevreden. Notably, the patient had a genetic predisposition to inflammatory bowel disease and reported recent use of nonsteroidal anti-inflammatory drugs, which may have increased his susceptibility to non-typhoidal Salmonella infection. The patient also developed myocarditis, making this the first reported case of Weltevreden-associated myocarditis in the region. Antimicrobial susceptibility testing indicated ciprofloxacin susceptibility, an increasingly rare finding, as most reported serovar Weltevreden cases exhibit ciprofloxacin resistance. The patient recovered following treatment with ciprofloxacin and was discharged with instructions for follow-up. This case highlights the need for heightened awareness of the potential for non-typhoidal Salmonella infections to cause systemic manifestations, even in individuals without major underlying comorbidities. Continuous monitoring of antimicrobial resistance patterns and strict food safety measures are essential to control outbreaks of these emerging pathogens.https://www.frontiersin.org/articles/10.3389/fmed.2025.1513974/fullnon-typhoidal SalmonellaSalmonella enterica serovar Weltevredenmyocarditisacute gastroenteritisciprofloxacin sensitive NTS |
| spellingShingle | Mahadevaiah Neelambike Sumana Morubagal Raghavendra Rao Vidyavathi B. Chitharagi Badveti Satyasai Supreeta R. Shettar Veerabhadra G. S. Swamy Chinchana S. Eshwarappa Yogeesh D. Maheshwarappa Myocarditis associated with Salmonella enterica serovar Weltevreden gastroenteritis in medical practitioner; case report from South India Frontiers in Medicine non-typhoidal Salmonella Salmonella enterica serovar Weltevreden myocarditis acute gastroenteritis ciprofloxacin sensitive NTS |
| title | Myocarditis associated with Salmonella enterica serovar Weltevreden gastroenteritis in medical practitioner; case report from South India |
| title_full | Myocarditis associated with Salmonella enterica serovar Weltevreden gastroenteritis in medical practitioner; case report from South India |
| title_fullStr | Myocarditis associated with Salmonella enterica serovar Weltevreden gastroenteritis in medical practitioner; case report from South India |
| title_full_unstemmed | Myocarditis associated with Salmonella enterica serovar Weltevreden gastroenteritis in medical practitioner; case report from South India |
| title_short | Myocarditis associated with Salmonella enterica serovar Weltevreden gastroenteritis in medical practitioner; case report from South India |
| title_sort | myocarditis associated with salmonella enterica serovar weltevreden gastroenteritis in medical practitioner case report from south india |
| topic | non-typhoidal Salmonella Salmonella enterica serovar Weltevreden myocarditis acute gastroenteritis ciprofloxacin sensitive NTS |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1513974/full |
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