QUALITATIVE AND QUANTITATIVE ANALISIS OF ORGANIC ACIDS IN MIXTURE OF MULTIVITAMIN RAW MATERIAL

The article presents the results of a qualitative analysis of organic acids in the mixture of the multivitamin raw material № 2. Thin layer chromatography method was confirmed to contain apple, citric and ascorbic acids. Quantitative analysis of the amount of organic acids and ascorbic acid was cond...

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Main Authors: V. Yu. Zhilkina, A. I. Marakhova, Ya. M. Stanishevskiy
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/234
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author V. Yu. Zhilkina
A. I. Marakhova
Ya. M. Stanishevskiy
author_facet V. Yu. Zhilkina
A. I. Marakhova
Ya. M. Stanishevskiy
author_sort V. Yu. Zhilkina
collection DOAJ
description The article presents the results of a qualitative analysis of organic acids in the mixture of the multivitamin raw material № 2. Thin layer chromatography method was confirmed to contain apple, citric and ascorbic acids. Quantitative analysis of the amount of organic acids and ascorbic acid was conducted by potentiometric titration method developed by the authors. The results were compared with the datas of the indicator titration and coulometry. The advantage of using a potentiometer to more accurately establish the endpoint was showed.
format Article
id doaj-art-9f897fba523b454fb69ee18b691a3cb9
institution Kabale University
issn 2305-2066
2658-5049
language Russian
publishDate 2019-01-01
publisher LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
record_format Article
series Разработка и регистрация лекарственных средств
spelling doaj-art-9f897fba523b454fb69ee18b691a3cb92025-08-20T03:59:20ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0101156159234QUALITATIVE AND QUANTITATIVE ANALISIS OF ORGANIC ACIDS IN MIXTURE OF MULTIVITAMIN RAW MATERIALV. Yu. Zhilkina0A. I. Marakhova1Ya. M. Stanishevskiy2Peoples' Friendship University of RussiaPeoples' Friendship University of RussiaPeoples' Friendship University of RussiaThe article presents the results of a qualitative analysis of organic acids in the mixture of the multivitamin raw material № 2. Thin layer chromatography method was confirmed to contain apple, citric and ascorbic acids. Quantitative analysis of the amount of organic acids and ascorbic acid was conducted by potentiometric titration method developed by the authors. The results were compared with the datas of the indicator titration and coulometry. The advantage of using a potentiometer to more accurately establish the endpoint was showed.https://www.pharmjournal.ru/jour/article/view/234potentiometrythe mixture of the multivitamin raw materialfructus rosaefructus sorbicoulometryorganic acidsascorbic acidthin layer chromatography
spellingShingle V. Yu. Zhilkina
A. I. Marakhova
Ya. M. Stanishevskiy
QUALITATIVE AND QUANTITATIVE ANALISIS OF ORGANIC ACIDS IN MIXTURE OF MULTIVITAMIN RAW MATERIAL
Разработка и регистрация лекарственных средств
potentiometry
the mixture of the multivitamin raw material
fructus rosae
fructus sorbi
coulometry
organic acids
ascorbic acid
thin layer chromatography
title QUALITATIVE AND QUANTITATIVE ANALISIS OF ORGANIC ACIDS IN MIXTURE OF MULTIVITAMIN RAW MATERIAL
title_full QUALITATIVE AND QUANTITATIVE ANALISIS OF ORGANIC ACIDS IN MIXTURE OF MULTIVITAMIN RAW MATERIAL
title_fullStr QUALITATIVE AND QUANTITATIVE ANALISIS OF ORGANIC ACIDS IN MIXTURE OF MULTIVITAMIN RAW MATERIAL
title_full_unstemmed QUALITATIVE AND QUANTITATIVE ANALISIS OF ORGANIC ACIDS IN MIXTURE OF MULTIVITAMIN RAW MATERIAL
title_short QUALITATIVE AND QUANTITATIVE ANALISIS OF ORGANIC ACIDS IN MIXTURE OF MULTIVITAMIN RAW MATERIAL
title_sort qualitative and quantitative analisis of organic acids in mixture of multivitamin raw material
topic potentiometry
the mixture of the multivitamin raw material
fructus rosae
fructus sorbi
coulometry
organic acids
ascorbic acid
thin layer chromatography
url https://www.pharmjournal.ru/jour/article/view/234
work_keys_str_mv AT vyuzhilkina qualitativeandquantitativeanalisisoforganicacidsinmixtureofmultivitaminrawmaterial
AT aimarakhova qualitativeandquantitativeanalisisoforganicacidsinmixtureofmultivitaminrawmaterial
AT yamstanishevskiy qualitativeandquantitativeanalisisoforganicacidsinmixtureofmultivitaminrawmaterial