liver disease. Clinical case of liver cirrhosis against the background of non-steroidal anti-inflammatory drugs

Drug lesions of the liver account for about 10% of all side reactions of the macrobody associated with the use of pharmacological preparations. The article describes the main mechanisms of drug injury to the liver. Diagnosis of drug liver damage is often difficult and requires the physician not only...

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Main Authors: E. Yu. Plotnikova, E. N. Baranova, O. A. Vorosova, M. S. Кaryagina, K. A. Krasnov
Format: Article
Language:Russian
Published: Open Systems Publication 2021-06-01
Series:Лечащий Врач
Subjects:
Online Access:https://journal.lvrach.ru/jour/article/view/82
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author E. Yu. Plotnikova
E. N. Baranova
O. A. Vorosova
M. S. Кaryagina
K. A. Krasnov
author_facet E. Yu. Plotnikova
E. N. Baranova
O. A. Vorosova
M. S. Кaryagina
K. A. Krasnov
author_sort E. Yu. Plotnikova
collection DOAJ
description Drug lesions of the liver account for about 10% of all side reactions of the macrobody associated with the use of pharmacological preparations. The article describes the main mechanisms of drug injury to the liver. Diagnosis of drug liver damage is often difficult and requires the physician not only to carefully collect the history of the patient with the developed disease, but also to have a good orientation in its clinical and morphological manifestations. A clinical case of drug cirrhosis of the liver is given, when the patient for many years overused various non-steroidal anti-inflammatory drugs, which led to a fatal outcome.
format Article
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institution DOAJ
issn 1560-5175
2687-1181
language Russian
publishDate 2021-06-01
publisher Open Systems Publication
record_format Article
series Лечащий Врач
spelling doaj-art-9f89456248c645048bdbdddf0c99ddb52025-08-20T03:19:57ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812021-06-0102283410.26295/OS.2020.67.71.00581liver disease. Clinical case of liver cirrhosis against the background of non-steroidal anti-inflammatory drugsE. Yu. Plotnikova0E. N. Baranova1O. A. Vorosova2M. S. Кaryagina3K. A. Krasnov4ФГБОУ ВО КемГМУ МЗ РФФГБОУ ВО КемГМУ МЗ РФФГБОУ ВО КемГМУ МЗ РФФГБОУ ВО КемГМУ МЗ РФФГБОУ ВО КемГМУ МЗ РФDrug lesions of the liver account for about 10% of all side reactions of the macrobody associated with the use of pharmacological preparations. The article describes the main mechanisms of drug injury to the liver. Diagnosis of drug liver damage is often difficult and requires the physician not only to carefully collect the history of the patient with the developed disease, but also to have a good orientation in its clinical and morphological manifestations. A clinical case of drug cirrhosis of the liver is given, when the patient for many years overused various non-steroidal anti-inflammatory drugs, which led to a fatal outcome.https://journal.lvrach.ru/jour/article/view/82drug-induced liver diseasenon-steroidal anti-inflammatory drugshepatotoxic drugscirrhosis of the liver
spellingShingle E. Yu. Plotnikova
E. N. Baranova
O. A. Vorosova
M. S. Кaryagina
K. A. Krasnov
liver disease. Clinical case of liver cirrhosis against the background of non-steroidal anti-inflammatory drugs
Лечащий Врач
drug-induced liver disease
non-steroidal anti-inflammatory drugs
hepatotoxic drugs
cirrhosis of the liver
title liver disease. Clinical case of liver cirrhosis against the background of non-steroidal anti-inflammatory drugs
title_full liver disease. Clinical case of liver cirrhosis against the background of non-steroidal anti-inflammatory drugs
title_fullStr liver disease. Clinical case of liver cirrhosis against the background of non-steroidal anti-inflammatory drugs
title_full_unstemmed liver disease. Clinical case of liver cirrhosis against the background of non-steroidal anti-inflammatory drugs
title_short liver disease. Clinical case of liver cirrhosis against the background of non-steroidal anti-inflammatory drugs
title_sort liver disease clinical case of liver cirrhosis against the background of non steroidal anti inflammatory drugs
topic drug-induced liver disease
non-steroidal anti-inflammatory drugs
hepatotoxic drugs
cirrhosis of the liver
url https://journal.lvrach.ru/jour/article/view/82
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AT enbaranova liverdiseaseclinicalcaseoflivercirrhosisagainstthebackgroundofnonsteroidalantiinflammatorydrugs
AT oavorosova liverdiseaseclinicalcaseoflivercirrhosisagainstthebackgroundofnonsteroidalantiinflammatorydrugs
AT mskaryagina liverdiseaseclinicalcaseoflivercirrhosisagainstthebackgroundofnonsteroidalantiinflammatorydrugs
AT kakrasnov liverdiseaseclinicalcaseoflivercirrhosisagainstthebackgroundofnonsteroidalantiinflammatorydrugs