Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury

Hyperostosis frontalis interna is an irregular thickening of the frontal bone. Its etiology is unknown. It has been rarely linked with schizophrenia and head injury. Case Presentation. We describe an unusual case of a 44-year-old female with schizophrenia and hyperostosis frontalis interna having a...

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Main Author: Fatima Elghazouani
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2021/6634640
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author Fatima Elghazouani
author_facet Fatima Elghazouani
author_sort Fatima Elghazouani
collection DOAJ
description Hyperostosis frontalis interna is an irregular thickening of the frontal bone. Its etiology is unknown. It has been rarely linked with schizophrenia and head injury. Case Presentation. We describe an unusual case of a 44-year-old female with schizophrenia and hyperostosis frontalis interna having a history of head trauma. At the age of 3 years, she had a head injury that could be classified as mild traumatic brain injury. She presents a family history of schizophrenia. She was admitted for resistant schizophrenic disorder. The cranial computed tomography showed bilateral and asymmetrical hyperostosis of the frontal bone that was more pronounced on the right side. This corresponds to the impact of the trauma with frontal atrophy without any metabolic or endocrinal abnormalities. Conclusion. We surmise that the long-term pathological effects of traumatic brain injury, including hyperostosis frontalis interna, are likely to interact with genetic vulnerability and may lead to schizophrenic disorder.
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spelling doaj-art-9f87e801c7b748c894276fb93581217d2025-02-03T07:24:00ZengWileyCase Reports in Medicine1687-96271687-96352021-01-01202110.1155/2021/66346406634640Schizophrenia and Hyperostosis Frontalis Interna with History of Head InjuryFatima Elghazouani0Department of Psychiatry, Materno-Infant and Mental Health Research Laboratory, Faculty of Medicine and Pharmacy, University Mohammed The First, Oujda, MoroccoHyperostosis frontalis interna is an irregular thickening of the frontal bone. Its etiology is unknown. It has been rarely linked with schizophrenia and head injury. Case Presentation. We describe an unusual case of a 44-year-old female with schizophrenia and hyperostosis frontalis interna having a history of head trauma. At the age of 3 years, she had a head injury that could be classified as mild traumatic brain injury. She presents a family history of schizophrenia. She was admitted for resistant schizophrenic disorder. The cranial computed tomography showed bilateral and asymmetrical hyperostosis of the frontal bone that was more pronounced on the right side. This corresponds to the impact of the trauma with frontal atrophy without any metabolic or endocrinal abnormalities. Conclusion. We surmise that the long-term pathological effects of traumatic brain injury, including hyperostosis frontalis interna, are likely to interact with genetic vulnerability and may lead to schizophrenic disorder.http://dx.doi.org/10.1155/2021/6634640
spellingShingle Fatima Elghazouani
Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury
Case Reports in Medicine
title Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury
title_full Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury
title_fullStr Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury
title_full_unstemmed Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury
title_short Schizophrenia and Hyperostosis Frontalis Interna with History of Head Injury
title_sort schizophrenia and hyperostosis frontalis interna with history of head injury
url http://dx.doi.org/10.1155/2021/6634640
work_keys_str_mv AT fatimaelghazouani schizophreniaandhyperostosisfrontalisinternawithhistoryofheadinjury