Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review
Introduction. Mild hypotension is a well-recognized complication of intravenous pentobarbital; however fulminant cardiopulmonary failure has not been previously reported. Case Report. A 28-year-old woman developed pentobarbital-induced cardiopulmonary failure that was successfully treated with maxim...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2016/1765165 |
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| _version_ | 1849398822166331392 |
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| author | Tapan Kavi Donna Molaie Michael Nurok Axel Rosengart Shouri Lahiri |
| author_facet | Tapan Kavi Donna Molaie Michael Nurok Axel Rosengart Shouri Lahiri |
| author_sort | Tapan Kavi |
| collection | DOAJ |
| description | Introduction. Mild hypotension is a well-recognized complication of intravenous pentobarbital; however fulminant cardiopulmonary failure has not been previously reported. Case Report. A 28-year-old woman developed pentobarbital-induced cardiopulmonary failure that was successfully treated with maximal medical management including arteriovenous extracorporeal membrane oxygenation. She made an excellent cardiopulmonary and neurological recovery. Discussion and Conclusion. Pentobarbital is underrecognized as a potential cause of myocardial stunning. The mechanism involves direct myocardial depression and inhibition of autonomic neuroanatomical structures including the medulla and hypothalamus. Early recognition and implementation of aggressive cardiopulmonary support are essential to optimize the likelihood of a favorable outcome. |
| format | Article |
| id | doaj-art-9f8089d58f4e4ff2a9274a5780c5f8b9 |
| institution | Kabale University |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-9f8089d58f4e4ff2a9274a5780c5f8b92025-08-20T03:38:30ZengWileyCase Reports in Critical Care2090-64202090-64392016-01-01201610.1155/2016/17651651765165Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature ReviewTapan Kavi0Donna Molaie1Michael Nurok2Axel Rosengart3Shouri Lahiri4Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Suite A6600, Los Angeles, CA 90048, USACedars-Sinai Medical Center, 127 South San Vicente Boulevard, Suite A6600, Los Angeles, CA 90048, USACedars-Sinai Medical Center, 127 South San Vicente Boulevard, Suite A6600, Los Angeles, CA 90048, USACedars-Sinai Medical Center, 127 South San Vicente Boulevard, Suite A6600, Los Angeles, CA 90048, USACedars-Sinai Medical Center, 127 South San Vicente Boulevard, Suite A6600, Los Angeles, CA 90048, USAIntroduction. Mild hypotension is a well-recognized complication of intravenous pentobarbital; however fulminant cardiopulmonary failure has not been previously reported. Case Report. A 28-year-old woman developed pentobarbital-induced cardiopulmonary failure that was successfully treated with maximal medical management including arteriovenous extracorporeal membrane oxygenation. She made an excellent cardiopulmonary and neurological recovery. Discussion and Conclusion. Pentobarbital is underrecognized as a potential cause of myocardial stunning. The mechanism involves direct myocardial depression and inhibition of autonomic neuroanatomical structures including the medulla and hypothalamus. Early recognition and implementation of aggressive cardiopulmonary support are essential to optimize the likelihood of a favorable outcome.http://dx.doi.org/10.1155/2016/1765165 |
| spellingShingle | Tapan Kavi Donna Molaie Michael Nurok Axel Rosengart Shouri Lahiri Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review Case Reports in Critical Care |
| title | Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review |
| title_full | Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review |
| title_fullStr | Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review |
| title_full_unstemmed | Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review |
| title_short | Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review |
| title_sort | pentobarbital induced myocardial stunning in status epilepticus requiring extracorporeal membrane oxygenation a case report and literature review |
| url | http://dx.doi.org/10.1155/2016/1765165 |
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