Treatment Choices in Women with Bipolar Disorder Seeking Pregnancy: A Clinical Case Illustration

After ten years of successful maintenance treatment with lithium and olanzapine, a 40-year-old woman with bipolar disorder expressed concerns about continuing the use of medicines, as she was planning a pregnancy. In the past, she had suffered from five severe manic episodes with hospital admissions...

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Main Authors: Corrado Barbui, Andrea Bertolazzi, Batul Hanife, Andrea Cipriani
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2013/630732
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author Corrado Barbui
Andrea Bertolazzi
Batul Hanife
Andrea Cipriani
author_facet Corrado Barbui
Andrea Bertolazzi
Batul Hanife
Andrea Cipriani
author_sort Corrado Barbui
collection DOAJ
description After ten years of successful maintenance treatment with lithium and olanzapine, a 40-year-old woman with bipolar disorder expressed concerns about continuing the use of medicines, as she was planning a pregnancy. In the past, she had suffered from five severe manic episodes with hospital admissions. After consultations with the treating psychiatrist, gynaecologist, and family doctor, olanzapine was stopped and lithium was gradually withdrawn. After few months, the patient, still in treatment with lithium 300 mg/die, experienced a new manic episode with hospital admission. Treatment with lithium and olanzapine was restored, and she progressively recovered. This case suggests that the risk of manic recurrence after ten years of maintenance treatment may be as high as the well-known risk of recurrence after few years of maintenance treatment, a consideration that doctors may find useful in the light of a complete absence of evidence on treatment choices after five years of successful maintenance treatment.
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series Case Reports in Psychiatry
spelling doaj-art-9f7f559b31e5420aa798e9022da29e812025-02-03T00:59:31ZengWileyCase Reports in Psychiatry2090-682X2090-68382013-01-01201310.1155/2013/630732630732Treatment Choices in Women with Bipolar Disorder Seeking Pregnancy: A Clinical Case IllustrationCorrado Barbui0Andrea Bertolazzi1Batul Hanife2Andrea Cipriani3WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Public Health and Community Medicine, Section of Psychiatry, University of Verona, Policlinico G.B. Rossi, Piazzale Scuro 10, 37134 Verona, ItalyWHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Public Health and Community Medicine, Section of Psychiatry, University of Verona, Policlinico G.B. Rossi, Piazzale Scuro 10, 37134 Verona, ItalyWHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Public Health and Community Medicine, Section of Psychiatry, University of Verona, Policlinico G.B. Rossi, Piazzale Scuro 10, 37134 Verona, ItalyWHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Public Health and Community Medicine, Section of Psychiatry, University of Verona, Policlinico G.B. Rossi, Piazzale Scuro 10, 37134 Verona, ItalyAfter ten years of successful maintenance treatment with lithium and olanzapine, a 40-year-old woman with bipolar disorder expressed concerns about continuing the use of medicines, as she was planning a pregnancy. In the past, she had suffered from five severe manic episodes with hospital admissions. After consultations with the treating psychiatrist, gynaecologist, and family doctor, olanzapine was stopped and lithium was gradually withdrawn. After few months, the patient, still in treatment with lithium 300 mg/die, experienced a new manic episode with hospital admission. Treatment with lithium and olanzapine was restored, and she progressively recovered. This case suggests that the risk of manic recurrence after ten years of maintenance treatment may be as high as the well-known risk of recurrence after few years of maintenance treatment, a consideration that doctors may find useful in the light of a complete absence of evidence on treatment choices after five years of successful maintenance treatment.http://dx.doi.org/10.1155/2013/630732
spellingShingle Corrado Barbui
Andrea Bertolazzi
Batul Hanife
Andrea Cipriani
Treatment Choices in Women with Bipolar Disorder Seeking Pregnancy: A Clinical Case Illustration
Case Reports in Psychiatry
title Treatment Choices in Women with Bipolar Disorder Seeking Pregnancy: A Clinical Case Illustration
title_full Treatment Choices in Women with Bipolar Disorder Seeking Pregnancy: A Clinical Case Illustration
title_fullStr Treatment Choices in Women with Bipolar Disorder Seeking Pregnancy: A Clinical Case Illustration
title_full_unstemmed Treatment Choices in Women with Bipolar Disorder Seeking Pregnancy: A Clinical Case Illustration
title_short Treatment Choices in Women with Bipolar Disorder Seeking Pregnancy: A Clinical Case Illustration
title_sort treatment choices in women with bipolar disorder seeking pregnancy a clinical case illustration
url http://dx.doi.org/10.1155/2013/630732
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