Bilateral rapidly destructive hip disease: a case report and literature review

Rapidly destructive hip disease (RDHD) is a rare syndrome marked by swift joint degeneration and substantial functional impairment, typically affecting a single hip joint. The occurrence of bilateral RDHD is exceptionally uncommon, highlighting the urgent need for further research into its pathogene...

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Main Authors: Yan Shen, Yi Zhang, Jing Fu, Hang Pei, Jiang Hua, Bangjian He
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1630171/full
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author Yan Shen
Yi Zhang
Jing Fu
Hang Pei
Jiang Hua
Bangjian He
author_facet Yan Shen
Yi Zhang
Jing Fu
Hang Pei
Jiang Hua
Bangjian He
author_sort Yan Shen
collection DOAJ
description Rapidly destructive hip disease (RDHD) is a rare syndrome marked by swift joint degeneration and substantial functional impairment, typically affecting a single hip joint. The occurrence of bilateral RDHD is exceptionally uncommon, highlighting the urgent need for further research into its pathogenesis, pathological changes, and treatment strategies. We present the case of a 75-year-old female who developed significant bilateral hip mobility limitations and buttock pain 6 months after being diagnosed with mild bilateral hip osteoarthritis. Imaging revealed the disappearance of both femoral heads. After excluding contraindications, the patient successfully underwent left uncemented total hip arthroplasty (THA). Postoperative pathology confirmed the diagnosis, showing degeneration and focal necrosis. This case represents the first documented instance of favorable clinical outcomes following THA in bilateral RDHD.
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spelling doaj-art-9f7e022046444ae99cd1963bf21fd1212025-08-20T03:36:38ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-08-011210.3389/fmed.2025.16301711630171Bilateral rapidly destructive hip disease: a case report and literature reviewYan Shen0Yi Zhang1Jing Fu2Hang Pei3Jiang Hua4Bangjian He5Huzhou Zhengbo Orthopedic Hospital, Huzhou, Zhejiang, ChinaZhejiang Chinese Medical University, Hangzhou, Zhejiang, ChinaDepartment of Stomatology, Xixi Hospital, Hangzhou, Zhejiang, ChinaZhejiang Chinese Medical University, Hangzhou, Zhejiang, ChinaDepartment of Orthopedics, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, ChinaDepartment of Orthopedics, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, ChinaRapidly destructive hip disease (RDHD) is a rare syndrome marked by swift joint degeneration and substantial functional impairment, typically affecting a single hip joint. The occurrence of bilateral RDHD is exceptionally uncommon, highlighting the urgent need for further research into its pathogenesis, pathological changes, and treatment strategies. We present the case of a 75-year-old female who developed significant bilateral hip mobility limitations and buttock pain 6 months after being diagnosed with mild bilateral hip osteoarthritis. Imaging revealed the disappearance of both femoral heads. After excluding contraindications, the patient successfully underwent left uncemented total hip arthroplasty (THA). Postoperative pathology confirmed the diagnosis, showing degeneration and focal necrosis. This case represents the first documented instance of favorable clinical outcomes following THA in bilateral RDHD.https://www.frontiersin.org/articles/10.3389/fmed.2025.1630171/fullbilateral rapidly destructive hip diseasetotal hip arthroplastyrheumatismcase reportliterature review
spellingShingle Yan Shen
Yi Zhang
Jing Fu
Hang Pei
Jiang Hua
Bangjian He
Bilateral rapidly destructive hip disease: a case report and literature review
Frontiers in Medicine
bilateral rapidly destructive hip disease
total hip arthroplasty
rheumatism
case report
literature review
title Bilateral rapidly destructive hip disease: a case report and literature review
title_full Bilateral rapidly destructive hip disease: a case report and literature review
title_fullStr Bilateral rapidly destructive hip disease: a case report and literature review
title_full_unstemmed Bilateral rapidly destructive hip disease: a case report and literature review
title_short Bilateral rapidly destructive hip disease: a case report and literature review
title_sort bilateral rapidly destructive hip disease a case report and literature review
topic bilateral rapidly destructive hip disease
total hip arthroplasty
rheumatism
case report
literature review
url https://www.frontiersin.org/articles/10.3389/fmed.2025.1630171/full
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AT jianghua bilateralrapidlydestructivehipdiseaseacasereportandliteraturereview
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