Infectious outcomes of a standardized subcutaneous immunoglobulin dose reduction strategy in primary immune deficiencies amid global shortage

Infectious outcomes of a standardized subcutaneous immunoglobulin dose reduction strategy in primary immune deficiencies amid global shortage

IntroductionImmunoglobulin replacement therapy (IgRT), either intravenous (IVIg) or subcutaneous (SCIg), is crucial for managing primary immune deficiencies (PIDs) with hypogammaglobulinemia by reducing infection rates and mortality. During the COVID-19 pandemic, a global shortage of SCIg prompted o...

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Bibliographic Details
Main Authors: Pedro Moral Moral, Marta Dafne Cabanero-Navalon, Paula Teresa López-León, Héctor Balastegui-Martín, Sandra Martínez Mercader, Amparo Mir, Victor Garcia-Bustos
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
immunoglobulin replacement therapy
humoral primary immune deficiencies
subcutaneous immunoglobulin
infections
cost-effectiveness
resource shortage
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1527514/full
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