Diagnosis and Treatment of Patients with Autoimmune Hepatitis (Experts’ Agreement)
Background. In the last decade, the understanding of the pathogenesis of autoimmune hepatitis (AIH) has significantly deepened, based on the results of new clinical studies some diagnostic issues have been revised and immunosuppressive therapy regimens have been optimized.Materials and methods. The...
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Gastro LLC
2025-02-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1468 |
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| author | Yu. G. Sandler E. V. Vinnitskaya K. L. Raikhelson K. V. Ivashkin S. N. Batskikh E. N. Aleksandrova D. T. Abdurakhmanov D. I. Abdulganieva I. G. Bakulin A. O. Bueverov S. L. Vorobyev O. A. Gerasimova A. I. Dolgushina M. S. Zhuravleva L. Yu. Ilchenko V. E. Karev N. V. Korochanskaya I. L. Kliaritskaia N. S. Karnaukhov S. V. Lapin M. A. Livzan M. V. Maevskaya N. V. Marchenko T. P. Nekrasova I. G. Nikitin A. A. Novikov R. G. Saifutdinov E. V. Skazyvaeva V. E. Syutkin M. K. Prashnova T. Yu. Khaymenova S. G. Khomerik |
| author_facet | Yu. G. Sandler E. V. Vinnitskaya K. L. Raikhelson K. V. Ivashkin S. N. Batskikh E. N. Aleksandrova D. T. Abdurakhmanov D. I. Abdulganieva I. G. Bakulin A. O. Bueverov S. L. Vorobyev O. A. Gerasimova A. I. Dolgushina M. S. Zhuravleva L. Yu. Ilchenko V. E. Karev N. V. Korochanskaya I. L. Kliaritskaia N. S. Karnaukhov S. V. Lapin M. A. Livzan M. V. Maevskaya N. V. Marchenko T. P. Nekrasova I. G. Nikitin A. A. Novikov R. G. Saifutdinov E. V. Skazyvaeva V. E. Syutkin M. K. Prashnova T. Yu. Khaymenova S. G. Khomerik |
| author_sort | Yu. G. Sandler |
| collection | DOAJ |
| description | Background. In the last decade, the understanding of the pathogenesis of autoimmune hepatitis (AIH) has significantly deepened, based on the results of new clinical studies some diagnostic issues have been revised and immunosuppressive therapy regimens have been optimized.Materials and methods. The latest Russian clinical guidelines for the diagnosis and treatment of AIH were presented in 2013; and in 2017, the first Russian agreement on the diagnosis and treatment of AIH was held. Updating approaches to the management of patients with AIH necessitated next systematization for use in clinical practice. In February 2024, the final session was held to discuss the provisions of the second agreement on the diagnosis and treatment of AIH.Results. This publication presents the main discussion points of the agreement regarding methods and algorithms for detecting autoantibodies, the role of liver biopsy, revised morphological criteria for AIH, optimized immunosuppressive therapy regimens, updated criteria for assessing the response to therapy.Conclusions. The agreement was the result of the work of a group of experts on the diagnosis and treatment of AIH and represents the basis for the creation of updated federal clinical guidelines. |
| format | Article |
| id | doaj-art-9f78d5136a924a139896e74db3d0df6e |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2025-02-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-9f78d5136a924a139896e74db3d0df6e2025-02-10T16:14:40ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732025-02-0134610011910.22416/1382-4376-2024-34-6-100-1191147Diagnosis and Treatment of Patients with Autoimmune Hepatitis (Experts’ Agreement)Yu. G. Sandler0E. V. Vinnitskaya1K. L. Raikhelson2K. V. Ivashkin3S. N. Batskikh4E. N. Aleksandrova5D. T. Abdurakhmanov6D. I. Abdulganieva7I. G. Bakulin8A. O. Bueverov9S. L. Vorobyev10O. A. Gerasimova11A. I. Dolgushina12M. S. Zhuravleva13L. Yu. Ilchenko14V. E. Karev15N. V. Korochanskaya16I. L. Kliaritskaia17N. S. Karnaukhov18S. V. Lapin19M. A. Livzan20M. V. Maevskaya21N. V. Marchenko22T. P. Nekrasova23I. G. Nikitin24A. A. Novikov25R. G. Saifutdinov26E. V. Skazyvaeva27V. E. Syutkin28M. K. Prashnova29T. Yu. Khaymenova30S. G. Khomerik31Loginov Moscow Clinical Scientific CenterLoginov Moscow Clinical Scientific CenterSaint Petersburg State UniversityI.M. Sechenov First Moscow State Medical University (Sechenov University)Loginov Moscow Clinical Scientific CenterLoginov Moscow Clinical Scientific CenterI.M. Sechenov First Moscow State Medical University (Sechenov University)Kazan State Medical UniversityNorth-Western State Medical University named after I.I. MechnikovI.M. Sechenov First Moscow State Medical University (Sechenov University)OOO National Center for Clinical Morphological DiagnosticsSaint Petersburg State University; Russian Scientific Center for Radiology and Surgical Technologies named after Academician A.M. GranovSouth Ural State Medical UniversityNorth-Western State Medical University named after I.I. MechnikovN.I. Pirogov Russian National Research Medical UniversityPediatric Research and Clinical Center for Infectious Diseases under the Federal Medical Biological AgencyKuban State Medical UniversityV.I. Vernadsky Crimean Federal UniversityLoginov Moscow Clinical Scientific CenterAcademician I.P. Pavlov First St. Petersburg State Medical UniversityOmsk State Medical UniversityI.M. Sechenov First Moscow State Medical University (Sechenov University)Russian Scientific Center for Radiology and Surgical Technologies named after Academician A.M. GranovI.M. Sechenov First Moscow State Medical University (Sechenov University)N.I. Pirogov Russian National Research Medical UniversityLoginov Moscow Clinical Scientific CenterKazan State Medical Academy — Branch Campus of the Russian Medical Academy of Continuous Professional EducationNorth-Western State Medical University named after I.I. MechnikovMedical and Biological University of Innovation and Continuous Education, State Research Center — Byrnasyan Federal Medical Biophysical Center of Federal Biological Agency; N.V. Sklifosovsky Research Institute for Emergency Care of the Moscow City Health DepartmentRussian Scientific Center for Radiology and Surgical Technologies named after Academician A.M. GranovLoginov Moscow Clinical Scientific CenterLoginov Moscow Clinical Scientific CenterBackground. In the last decade, the understanding of the pathogenesis of autoimmune hepatitis (AIH) has significantly deepened, based on the results of new clinical studies some diagnostic issues have been revised and immunosuppressive therapy regimens have been optimized.Materials and methods. The latest Russian clinical guidelines for the diagnosis and treatment of AIH were presented in 2013; and in 2017, the first Russian agreement on the diagnosis and treatment of AIH was held. Updating approaches to the management of patients with AIH necessitated next systematization for use in clinical practice. In February 2024, the final session was held to discuss the provisions of the second agreement on the diagnosis and treatment of AIH.Results. This publication presents the main discussion points of the agreement regarding methods and algorithms for detecting autoantibodies, the role of liver biopsy, revised morphological criteria for AIH, optimized immunosuppressive therapy regimens, updated criteria for assessing the response to therapy.Conclusions. The agreement was the result of the work of a group of experts on the diagnosis and treatment of AIH and represents the basis for the creation of updated federal clinical guidelines.https://www.gastro-j.ru/jour/article/view/1468autoimmune hepatitisagreementautoantibodiesimmunosuppressive therapyfederal clinical guidelines |
| spellingShingle | Yu. G. Sandler E. V. Vinnitskaya K. L. Raikhelson K. V. Ivashkin S. N. Batskikh E. N. Aleksandrova D. T. Abdurakhmanov D. I. Abdulganieva I. G. Bakulin A. O. Bueverov S. L. Vorobyev O. A. Gerasimova A. I. Dolgushina M. S. Zhuravleva L. Yu. Ilchenko V. E. Karev N. V. Korochanskaya I. L. Kliaritskaia N. S. Karnaukhov S. V. Lapin M. A. Livzan M. V. Maevskaya N. V. Marchenko T. P. Nekrasova I. G. Nikitin A. A. Novikov R. G. Saifutdinov E. V. Skazyvaeva V. E. Syutkin M. K. Prashnova T. Yu. Khaymenova S. G. Khomerik Diagnosis and Treatment of Patients with Autoimmune Hepatitis (Experts’ Agreement) Российский журнал гастроэнтерологии, гепатологии, колопроктологии autoimmune hepatitis agreement autoantibodies immunosuppressive therapy federal clinical guidelines |
| title | Diagnosis and Treatment of Patients with Autoimmune Hepatitis (Experts’ Agreement) |
| title_full | Diagnosis and Treatment of Patients with Autoimmune Hepatitis (Experts’ Agreement) |
| title_fullStr | Diagnosis and Treatment of Patients with Autoimmune Hepatitis (Experts’ Agreement) |
| title_full_unstemmed | Diagnosis and Treatment of Patients with Autoimmune Hepatitis (Experts’ Agreement) |
| title_short | Diagnosis and Treatment of Patients with Autoimmune Hepatitis (Experts’ Agreement) |
| title_sort | diagnosis and treatment of patients with autoimmune hepatitis experts agreement |
| topic | autoimmune hepatitis agreement autoantibodies immunosuppressive therapy federal clinical guidelines |
| url | https://www.gastro-j.ru/jour/article/view/1468 |
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