Evaluation of retinal pigment epithelium changes in serous pigment epithelial detachment using synthesized multi-contrast polarization-sensitive optical coherence tomography

Evaluation of retinal pigment epithelium changes in serous pigment epithelial detachment using synthesized multi-contrast polarization-sensitive optical coherence tomography

Abstract Retinal pigment epithelium (RPE) melanin thickness maps, derived from multi-contrast images—including the degree of polarization uniformity (DOPU), optical coherence tomography (OCT) angiography, and the attenuation coefficient—are obtained using multi-contrast polarization-sensitive OCT (P...

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Bibliographic Details
Main Authors:	Kosei Yanagida, Masahiro Miura, Hidetaka Noma, Toshihiro Mino, Shinnosuke Azuma, Thitiya Seesan, Shuichi Makita, Yoshiaki Yasuno
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-07-01
Series:	Scientific Reports
Subjects:	Polarization-sensitive optical coherence tomography Convolutional neural network Retinal pigment epithelium Melanin Age-related macular degeneration Pigment epithelial detachment
Online Access:	https://doi.org/10.1038/s41598-025-09302-6
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