The Influence of Palatable Diets in Reward System Activation: A Mini Review
The changes in eating patterns that have occurred in recent decades are an important cause of obesity. Food intake and energy expenditure are controlled by a complex neural system involving the hypothalamic centers and peripheral satiety system (gastrointestinal and pancreatic hormones). Highly pala...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Advances in Pharmacological Sciences |
| Online Access: | http://dx.doi.org/10.1155/2016/7238679 |
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| author | Isabel Cristina de Macedo Joice Soares de Freitas Iraci Lucena da Silva Torres |
| author_facet | Isabel Cristina de Macedo Joice Soares de Freitas Iraci Lucena da Silva Torres |
| author_sort | Isabel Cristina de Macedo |
| collection | DOAJ |
| description | The changes in eating patterns that have occurred in recent decades are an important cause of obesity. Food intake and energy expenditure are controlled by a complex neural system involving the hypothalamic centers and peripheral satiety system (gastrointestinal and pancreatic hormones). Highly palatable and caloric food disrupts appetite regulation; however, palatable foods induce pleasure and reward. The cafeteria diet is such a palatable diet and has been shown consistently to increase body weight and induce hyperplasia in animal obesity models. Moreover, palatable high-fat foods (such as those of the cafeteria diet) can induce addiction-like deficits in brain reward function and are considered to be an important source of motivation that might drive overeating and contribute to the development of obesity. The mechanism of neural adaptation triggered by palatable foods is similar to those that have been reported for nondrug addictions and long-term drug use. Thus, this review attempts to describe the potential mechanisms that might lead to highly palatable diets, such as the cafeteria diet, triggering addiction, or compulsion through the reward system. |
| format | Article |
| id | doaj-art-9f752864ada24136ac63de33f3b67f8e |
| institution | Kabale University |
| issn | 1687-6334 1687-6342 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Pharmacological Sciences |
| spelling | doaj-art-9f752864ada24136ac63de33f3b67f8e2025-02-03T01:11:26ZengWileyAdvances in Pharmacological Sciences1687-63341687-63422016-01-01201610.1155/2016/72386797238679The Influence of Palatable Diets in Reward System Activation: A Mini ReviewIsabel Cristina de Macedo0Joice Soares de Freitas1Iraci Lucena da Silva Torres2Pharmacology of Pain and Neuromodulation Laboratory: Animal Models, Department of Pharmacology, Universidade Federal do Rio Grande do Sul, Institute of Basic Health Sciences, 90050-170 Porto Alegre, RS, BrazilPharmacology of Pain and Neuromodulation Laboratory: Animal Models, Department of Pharmacology, Universidade Federal do Rio Grande do Sul, Institute of Basic Health Sciences, 90050-170 Porto Alegre, RS, BrazilPharmacology of Pain and Neuromodulation Laboratory: Animal Models, Department of Pharmacology, Universidade Federal do Rio Grande do Sul, Institute of Basic Health Sciences, 90050-170 Porto Alegre, RS, BrazilThe changes in eating patterns that have occurred in recent decades are an important cause of obesity. Food intake and energy expenditure are controlled by a complex neural system involving the hypothalamic centers and peripheral satiety system (gastrointestinal and pancreatic hormones). Highly palatable and caloric food disrupts appetite regulation; however, palatable foods induce pleasure and reward. The cafeteria diet is such a palatable diet and has been shown consistently to increase body weight and induce hyperplasia in animal obesity models. Moreover, palatable high-fat foods (such as those of the cafeteria diet) can induce addiction-like deficits in brain reward function and are considered to be an important source of motivation that might drive overeating and contribute to the development of obesity. The mechanism of neural adaptation triggered by palatable foods is similar to those that have been reported for nondrug addictions and long-term drug use. Thus, this review attempts to describe the potential mechanisms that might lead to highly palatable diets, such as the cafeteria diet, triggering addiction, or compulsion through the reward system.http://dx.doi.org/10.1155/2016/7238679 |
| spellingShingle | Isabel Cristina de Macedo Joice Soares de Freitas Iraci Lucena da Silva Torres The Influence of Palatable Diets in Reward System Activation: A Mini Review Advances in Pharmacological Sciences |
| title | The Influence of Palatable Diets in Reward System Activation: A Mini Review |
| title_full | The Influence of Palatable Diets in Reward System Activation: A Mini Review |
| title_fullStr | The Influence of Palatable Diets in Reward System Activation: A Mini Review |
| title_full_unstemmed | The Influence of Palatable Diets in Reward System Activation: A Mini Review |
| title_short | The Influence of Palatable Diets in Reward System Activation: A Mini Review |
| title_sort | influence of palatable diets in reward system activation a mini review |
| url | http://dx.doi.org/10.1155/2016/7238679 |
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