The Lao Experience in Deploying Influenza A(H1N1)pdm09 Vaccine: Lessons Made Relevant in Preparing for Present Day Pandemic Threats.
The Lao PDR, as did most countries of the Mekong Region, embarked on a pandemic vaccine initiative to counter the threat posed by influenza A(H1N1)pdm09. Overall, estimated vaccine coverage of the Lao population was 14%, with uptake in targeted health care workers and pregnant women 99% and 41%, res...
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0121717 |
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| author | Anonh Xeuatvongsa Sara Mirza Christian Winter Keith Feldon Phengta Vongphrachanh Darouny Phonekeo Justin Denny Viengphone Khanthamaly Bounheuang Kounnavong Doualy Lylianou Sisouphane Phousavath Sisouveth Norasingh Nao Boutta Sonja Olsen Joseph Bresee Ann Moen Andrew Corwin |
| author_facet | Anonh Xeuatvongsa Sara Mirza Christian Winter Keith Feldon Phengta Vongphrachanh Darouny Phonekeo Justin Denny Viengphone Khanthamaly Bounheuang Kounnavong Doualy Lylianou Sisouphane Phousavath Sisouveth Norasingh Nao Boutta Sonja Olsen Joseph Bresee Ann Moen Andrew Corwin |
| author_sort | Anonh Xeuatvongsa |
| collection | DOAJ |
| description | The Lao PDR, as did most countries of the Mekong Region, embarked on a pandemic vaccine initiative to counter the threat posed by influenza A(H1N1)pdm09. Overall, estimated vaccine coverage of the Lao population was 14%, with uptake in targeted health care workers and pregnant women 99% and 41%, respectively. Adverse Events Following Immunization accounted for only 6% of survey driven, reported vaccination experiences, with no severe consequences or deaths. Public acceptability of the vaccine campaign was high (98%). Challenges to vaccine deployment included: 1) no previous experience in fielding a seasonal influenza vaccine, 2) safety and efficacy concerns, and 3) late arrival of vaccine 10 months into the pandemic. The Lao success in surmounting these hurdles was in large measure attributed to the oversight assigned the National Immunization Program, and national sensitivities in responding to the avian influenza A(H5N1) crisis in the years leading up to the pandemic. The Lao "lessons learned" from pandemic vaccine deployment are made even more relevant four years on, given the many avian influenza strains circulating in the region, all with pandemic potential. |
| format | Article |
| id | doaj-art-9f65d046a6ae4cc08b4d52bcdafdf7b2 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-9f65d046a6ae4cc08b4d52bcdafdf7b22025-08-20T02:22:40ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01104e012171710.1371/journal.pone.0121717The Lao Experience in Deploying Influenza A(H1N1)pdm09 Vaccine: Lessons Made Relevant in Preparing for Present Day Pandemic Threats.Anonh XeuatvongsaSara MirzaChristian WinterKeith FeldonPhengta VongphrachanhDarouny PhonekeoJustin DennyViengphone KhanthamalyBounheuang KounnavongDoualy LylianouSisouphane PhousavathSisouveth NorasinghNao BouttaSonja OlsenJoseph BreseeAnn MoenAndrew CorwinThe Lao PDR, as did most countries of the Mekong Region, embarked on a pandemic vaccine initiative to counter the threat posed by influenza A(H1N1)pdm09. Overall, estimated vaccine coverage of the Lao population was 14%, with uptake in targeted health care workers and pregnant women 99% and 41%, respectively. Adverse Events Following Immunization accounted for only 6% of survey driven, reported vaccination experiences, with no severe consequences or deaths. Public acceptability of the vaccine campaign was high (98%). Challenges to vaccine deployment included: 1) no previous experience in fielding a seasonal influenza vaccine, 2) safety and efficacy concerns, and 3) late arrival of vaccine 10 months into the pandemic. The Lao success in surmounting these hurdles was in large measure attributed to the oversight assigned the National Immunization Program, and national sensitivities in responding to the avian influenza A(H5N1) crisis in the years leading up to the pandemic. The Lao "lessons learned" from pandemic vaccine deployment are made even more relevant four years on, given the many avian influenza strains circulating in the region, all with pandemic potential.https://doi.org/10.1371/journal.pone.0121717 |
| spellingShingle | Anonh Xeuatvongsa Sara Mirza Christian Winter Keith Feldon Phengta Vongphrachanh Darouny Phonekeo Justin Denny Viengphone Khanthamaly Bounheuang Kounnavong Doualy Lylianou Sisouphane Phousavath Sisouveth Norasingh Nao Boutta Sonja Olsen Joseph Bresee Ann Moen Andrew Corwin The Lao Experience in Deploying Influenza A(H1N1)pdm09 Vaccine: Lessons Made Relevant in Preparing for Present Day Pandemic Threats. PLoS ONE |
| title | The Lao Experience in Deploying Influenza A(H1N1)pdm09 Vaccine: Lessons Made Relevant in Preparing for Present Day Pandemic Threats. |
| title_full | The Lao Experience in Deploying Influenza A(H1N1)pdm09 Vaccine: Lessons Made Relevant in Preparing for Present Day Pandemic Threats. |
| title_fullStr | The Lao Experience in Deploying Influenza A(H1N1)pdm09 Vaccine: Lessons Made Relevant in Preparing for Present Day Pandemic Threats. |
| title_full_unstemmed | The Lao Experience in Deploying Influenza A(H1N1)pdm09 Vaccine: Lessons Made Relevant in Preparing for Present Day Pandemic Threats. |
| title_short | The Lao Experience in Deploying Influenza A(H1N1)pdm09 Vaccine: Lessons Made Relevant in Preparing for Present Day Pandemic Threats. |
| title_sort | lao experience in deploying influenza a h1n1 pdm09 vaccine lessons made relevant in preparing for present day pandemic threats |
| url | https://doi.org/10.1371/journal.pone.0121717 |
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