MyoD is required for the differentiation of Myo/Nog cell progenitors of myofibroblasts in explants of human lens tissue

MyoD is required for the differentiation of Myo/Nog cell progenitors of myofibroblasts in explants of human lens tissue

IntroductionPosterior capsule opacification (PCO) is a complication of cataract surgery that impairs vision. Clouding and distortion of the posterior capsule occur as a result of cell migration, deposition of extracellular matrix proteins and contractions of myofibroblasts. The focus of this study i...

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Bibliographic Details
Main Authors: Jacquelyn Gerhart, Mara Crispin, Brian Heist, Keith Mathers, Joseph Infanti, David Venuti, Joseph F. Richards, Steven Morency, Cathy Hatcher, Mindy George-Weinstein
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Ophthalmology
Subjects:
posterior capsule opacification
lens
myofibroblasts
MyoD
Myo/Nog cells
Online Access:https://www.frontiersin.org/articles/10.3389/fopht.2025.1618276/full
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