Fiberoptic Bronchoscopic Findings in Patients Suffering from Emerging Pulmonary Lophomoniasis: A First Registry-Based Clinical Study

Background. Lophomonas blattarum is an emerging protozoan agent that mainly infects the lower respiratory system, causing pulmonary lophomoniasis. The bronchoscopic findings in patients with pulmonary lophomoniasis have not been investigated yet. Accordingly, we assess the bronchoscopic findings of...

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Main Authors: Masoud Aliyali, Amirmasoud Taheri, Mahdi Fakhar, Ali Sharifpour, Maryam Nakhaei, Siavash Abedi, Hossein Mehravaran, Sepideh Safanavaei
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Interdisciplinary Perspectives on Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2022/8034295
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author Masoud Aliyali
Amirmasoud Taheri
Mahdi Fakhar
Ali Sharifpour
Maryam Nakhaei
Siavash Abedi
Hossein Mehravaran
Sepideh Safanavaei
author_facet Masoud Aliyali
Amirmasoud Taheri
Mahdi Fakhar
Ali Sharifpour
Maryam Nakhaei
Siavash Abedi
Hossein Mehravaran
Sepideh Safanavaei
author_sort Masoud Aliyali
collection DOAJ
description Background. Lophomonas blattarum is an emerging protozoan agent that mainly infects the lower respiratory system, causing pulmonary lophomoniasis. The bronchoscopic findings in patients with pulmonary lophomoniasis have not been investigated yet. Accordingly, we assess the bronchoscopic findings of lophomoniasis in patients suffering from pulmonary lophomoniasis through a registry-based clinical study. Methods. In this retrospective study, of 480 patient candidates for bronchoscopy, 50 Lophomonas-positive patients were enrolled. Demographic data, relevant characteristics, and bronchoscopy findings of the patients were recorded and analyzed. Results. Overall, 50 (male = 32, female = 18) patients with an average age of 61.8 ± 13.3 years were examined. Nineteen patients (38%) had normal bronchoscopic findings, and 31 patients (62%) had abnormal bronchoscopic findings. According to the severity index, most (52%) of patients had mild severity, followed by moderate (30%) and severe (18%) cases. The highest involvement was in the right lung bronchus (46%), and the lowest was in the carina (8%). Furthermore, purulent and mucosal secretions in the right and left lung bronchus were the most abnormalities found in different anatomical locations. Conclusion. For the first time, the current study demonstrated that pulmonary lophomoniasis does not have pathognomonic bronchoscopic findings. However, each suspected patient must be checked for lophomoniasis, even with normal bronchoscopic findings, particularly in endemic areas.
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spelling doaj-art-9f61d91d170e451fade9b5dd7d2b53e12025-08-20T03:38:30ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-70982022-01-01202210.1155/2022/8034295Fiberoptic Bronchoscopic Findings in Patients Suffering from Emerging Pulmonary Lophomoniasis: A First Registry-Based Clinical StudyMasoud Aliyali0Amirmasoud Taheri1Mahdi Fakhar2Ali Sharifpour3Maryam Nakhaei4Siavash Abedi5Hossein Mehravaran6Sepideh Safanavaei7Toxoplasmosis Research CenterToxoplasmosis Research CenterToxoplasmosis Research CenterToxoplasmosis Research CenterToxoplasmosis Research CenterToxoplasmosis Research CenterToxoplasmosis Research CenterToxoplasmosis Research CenterBackground. Lophomonas blattarum is an emerging protozoan agent that mainly infects the lower respiratory system, causing pulmonary lophomoniasis. The bronchoscopic findings in patients with pulmonary lophomoniasis have not been investigated yet. Accordingly, we assess the bronchoscopic findings of lophomoniasis in patients suffering from pulmonary lophomoniasis through a registry-based clinical study. Methods. In this retrospective study, of 480 patient candidates for bronchoscopy, 50 Lophomonas-positive patients were enrolled. Demographic data, relevant characteristics, and bronchoscopy findings of the patients were recorded and analyzed. Results. Overall, 50 (male = 32, female = 18) patients with an average age of 61.8 ± 13.3 years were examined. Nineteen patients (38%) had normal bronchoscopic findings, and 31 patients (62%) had abnormal bronchoscopic findings. According to the severity index, most (52%) of patients had mild severity, followed by moderate (30%) and severe (18%) cases. The highest involvement was in the right lung bronchus (46%), and the lowest was in the carina (8%). Furthermore, purulent and mucosal secretions in the right and left lung bronchus were the most abnormalities found in different anatomical locations. Conclusion. For the first time, the current study demonstrated that pulmonary lophomoniasis does not have pathognomonic bronchoscopic findings. However, each suspected patient must be checked for lophomoniasis, even with normal bronchoscopic findings, particularly in endemic areas.http://dx.doi.org/10.1155/2022/8034295
spellingShingle Masoud Aliyali
Amirmasoud Taheri
Mahdi Fakhar
Ali Sharifpour
Maryam Nakhaei
Siavash Abedi
Hossein Mehravaran
Sepideh Safanavaei
Fiberoptic Bronchoscopic Findings in Patients Suffering from Emerging Pulmonary Lophomoniasis: A First Registry-Based Clinical Study
Interdisciplinary Perspectives on Infectious Diseases
title Fiberoptic Bronchoscopic Findings in Patients Suffering from Emerging Pulmonary Lophomoniasis: A First Registry-Based Clinical Study
title_full Fiberoptic Bronchoscopic Findings in Patients Suffering from Emerging Pulmonary Lophomoniasis: A First Registry-Based Clinical Study
title_fullStr Fiberoptic Bronchoscopic Findings in Patients Suffering from Emerging Pulmonary Lophomoniasis: A First Registry-Based Clinical Study
title_full_unstemmed Fiberoptic Bronchoscopic Findings in Patients Suffering from Emerging Pulmonary Lophomoniasis: A First Registry-Based Clinical Study
title_short Fiberoptic Bronchoscopic Findings in Patients Suffering from Emerging Pulmonary Lophomoniasis: A First Registry-Based Clinical Study
title_sort fiberoptic bronchoscopic findings in patients suffering from emerging pulmonary lophomoniasis a first registry based clinical study
url http://dx.doi.org/10.1155/2022/8034295
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