Spatial Resolution of a small animal PET scanner using 68Ga isotope

Nuclear Medicine is a modality that has been growing a lot in Brazil and in the world, bringing new radiopharmaceuticals and technologies for the diagnosis and treatment of diseases, making them more effective and accurate. In the development of new radiopharmaceuticals for use in positron emission...

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Main Authors: Victoria M. Garcia, A. C. M. Silva, Rodrigo Modesto Gadelha Gontijo, Andréa Vidal Ferreira
Format: Article
Language:English
Published: Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) 2024-04-01
Series:Brazilian Journal of Radiation Sciences
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Online Access:https://bjrs.org.br/revista/index.php/REVISTA/article/view/2404
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author Victoria M. Garcia
A. C. M. Silva
Rodrigo Modesto Gadelha Gontijo
Andréa Vidal Ferreira
author_facet Victoria M. Garcia
A. C. M. Silva
Rodrigo Modesto Gadelha Gontijo
Andréa Vidal Ferreira
author_sort Victoria M. Garcia
collection DOAJ
description Nuclear Medicine is a modality that has been growing a lot in Brazil and in the world, bringing new radiopharmaceuticals and technologies for the diagnosis and treatment of diseases, making them more effective and accurate. In the development of new radiopharmaceuticals for use in positron emission tomography (PET), the preclinical studies step largely uses PET scanners dedicated to small animals. To achieve this, quality control tests must be carried out to ensure the efficiency of the equipment. Thus, this work aimed to evaluate the spatial resolution of the small animals PET scanner of the CDTN using the isotope 68Ga. In this sense, a microPET hot rod phantom and a commercial 68Ge/68Ga generator were used to obtain PET images. The analysis of the 68Ga-PET images of the simulator was carried out qualitatively and quantitatively and revealed that the spatial resolution of the system using the 68Ga is 3.5 mm.
format Article
id doaj-art-9f5dd6fbf7bd4463b8e2c216ed6a3d99
institution DOAJ
issn 2319-0612
language English
publishDate 2024-04-01
publisher Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)
record_format Article
series Brazilian Journal of Radiation Sciences
spelling doaj-art-9f5dd6fbf7bd4463b8e2c216ed6a3d992025-08-20T03:13:30ZengBrazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)Brazilian Journal of Radiation Sciences2319-06122024-04-01122e2404e240410.15392/2319-0612.2024.24042027Spatial Resolution of a small animal PET scanner using 68Ga isotopeVictoria M. Garcia0A. C. M. Silva1Rodrigo Modesto Gadelha Gontijo2Andréa Vidal Ferreira3Centro de Desenvolvimento da Tecnologia NuclearCentro de Desenvolvimento da Tecnologia NuclearCentro de Desenvolvimento da Tecnologia Nuclear / UFMG / EBSERHCentro de Desenvolvimento da Tecnologia NuclearNuclear Medicine is a modality that has been growing a lot in Brazil and in the world, bringing new radiopharmaceuticals and technologies for the diagnosis and treatment of diseases, making them more effective and accurate. In the development of new radiopharmaceuticals for use in positron emission tomography (PET), the preclinical studies step largely uses PET scanners dedicated to small animals. To achieve this, quality control tests must be carried out to ensure the efficiency of the equipment. Thus, this work aimed to evaluate the spatial resolution of the small animals PET scanner of the CDTN using the isotope 68Ga. In this sense, a microPET hot rod phantom and a commercial 68Ge/68Ga generator were used to obtain PET images. The analysis of the 68Ga-PET images of the simulator was carried out qualitatively and quantitatively and revealed that the spatial resolution of the system using the 68Ga is 3.5 mm.https://bjrs.org.br/revista/index.php/REVISTA/article/view/2404positron emission tomographypetquality controlspatial resolution68ga
spellingShingle Victoria M. Garcia
A. C. M. Silva
Rodrigo Modesto Gadelha Gontijo
Andréa Vidal Ferreira
Spatial Resolution of a small animal PET scanner using 68Ga isotope
Brazilian Journal of Radiation Sciences
positron emission tomography
pet
quality control
spatial resolution
68ga
title Spatial Resolution of a small animal PET scanner using 68Ga isotope
title_full Spatial Resolution of a small animal PET scanner using 68Ga isotope
title_fullStr Spatial Resolution of a small animal PET scanner using 68Ga isotope
title_full_unstemmed Spatial Resolution of a small animal PET scanner using 68Ga isotope
title_short Spatial Resolution of a small animal PET scanner using 68Ga isotope
title_sort spatial resolution of a small animal pet scanner using 68ga isotope
topic positron emission tomography
pet
quality control
spatial resolution
68ga
url https://bjrs.org.br/revista/index.php/REVISTA/article/view/2404
work_keys_str_mv AT victoriamgarcia spatialresolutionofasmallanimalpetscannerusing68gaisotope
AT acmsilva spatialresolutionofasmallanimalpetscannerusing68gaisotope
AT rodrigomodestogadelhagontijo spatialresolutionofasmallanimalpetscannerusing68gaisotope
AT andreavidalferreira spatialresolutionofasmallanimalpetscannerusing68gaisotope