Primary Bilateral Non-Hodgkin’s Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses
Although lymphoma may occasionally involve the adrenal glands as part of a generalized disease process, primary adrenal lymphoma (PAL) is a rare disease. We present a case of a 62-year-old woman with a history of mild/moderate hereditary spherocytosis with a well-compensated baseline haemoglobin, wh...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/620381 |
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| author | Christopher Rizzo David James Camilleri Alexandra Betts Andre’ Gatt Stephen Fava |
| author_facet | Christopher Rizzo David James Camilleri Alexandra Betts Andre’ Gatt Stephen Fava |
| author_sort | Christopher Rizzo |
| collection | DOAJ |
| description | Although lymphoma may occasionally involve the adrenal glands as part of a generalized disease process, primary adrenal lymphoma (PAL) is a rare disease. We present a case of a 62-year-old woman with a history of mild/moderate hereditary spherocytosis with a well-compensated baseline haemoglobin, who presented with rapidly progressive symptomatic anaemia. During the diagnostic workup, imaging revealed bilateral large adrenal masses and she was later diagnosed with diffuse large B-cell non-Hodgkin’s lymphoma (DLBCL), with the adrenal glands being the dominant site of the disease. The patient was started on systemic chemotherapy, but her disease progressed with neurological involvement which responded to second-line therapy. Her adrenal disease however was refractory to further therapy. |
| format | Article |
| id | doaj-art-9f5adb03ebfa4772b401d4a5affe2abe |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-9f5adb03ebfa4772b401d4a5affe2abe2025-02-03T01:07:46ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/620381620381Primary Bilateral Non-Hodgkin’s Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal MassesChristopher Rizzo0David James Camilleri1Alexandra Betts2Andre’ Gatt3Stephen Fava4Diabetes and Endocrine Centre, Mater Dei Hospital, Msida MSD 2090, MaltaDepartment of Haemato-Oncology, Mater Dei Hospital, Msida MSD 2090, MaltaHistopathology Section, Pathology Department, Mater Dei Hospital, Msida MSD 2090, MaltaMedical Imaging Department, Mater Dei Hospital, Msida MSD 2090, MaltaDiabetes and Endocrine Centre, Mater Dei Hospital, Msida MSD 2090, MaltaAlthough lymphoma may occasionally involve the adrenal glands as part of a generalized disease process, primary adrenal lymphoma (PAL) is a rare disease. We present a case of a 62-year-old woman with a history of mild/moderate hereditary spherocytosis with a well-compensated baseline haemoglobin, who presented with rapidly progressive symptomatic anaemia. During the diagnostic workup, imaging revealed bilateral large adrenal masses and she was later diagnosed with diffuse large B-cell non-Hodgkin’s lymphoma (DLBCL), with the adrenal glands being the dominant site of the disease. The patient was started on systemic chemotherapy, but her disease progressed with neurological involvement which responded to second-line therapy. Her adrenal disease however was refractory to further therapy.http://dx.doi.org/10.1155/2015/620381 |
| spellingShingle | Christopher Rizzo David James Camilleri Alexandra Betts Andre’ Gatt Stephen Fava Primary Bilateral Non-Hodgkin’s Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses Case Reports in Medicine |
| title | Primary Bilateral Non-Hodgkin’s Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses |
| title_full | Primary Bilateral Non-Hodgkin’s Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses |
| title_fullStr | Primary Bilateral Non-Hodgkin’s Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses |
| title_full_unstemmed | Primary Bilateral Non-Hodgkin’s Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses |
| title_short | Primary Bilateral Non-Hodgkin’s Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses |
| title_sort | primary bilateral non hodgkin s lymphoma of the adrenal gland presenting as incidental adrenal masses |
| url | http://dx.doi.org/10.1155/2015/620381 |
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