Chronic musculoskeletal pain. Leading symptom or comorbid pathology?
Current trends in the development of personalized medicine dictate the need to interpret chronic pain as a multifactorial biopsychosocial phenomenon. A comprehensive integrated approach to the management of patients with chronic pain includes nosological diagnostics, assessment of factors that deter...
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2022-06-01
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| Series: | Современная ревматология |
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| Online Access: | https://mrj.ima-press.net/mrj/article/view/1305 |
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| _version_ | 1849242142574116864 |
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| author | Yu. A. Olyunin |
| author_facet | Yu. A. Olyunin |
| author_sort | Yu. A. Olyunin |
| collection | DOAJ |
| description | Current trends in the development of personalized medicine dictate the need to interpret chronic pain as a multifactorial biopsychosocial phenomenon. A comprehensive integrated approach to the management of patients with chronic pain includes nosological diagnostics, assessment of factors that determine the persistence of pain and comorbid pathology, and the use of necessary pharmacological and non-pharmacological methods of treatment. Currently, primarily non-steroidal anti-inflammatory drugs are used for the pharmacotherapy of chronic pain, which is predominantly nociceptive in nature. Meloxicam (Movalis®), along with high efficacy, has a favorable safety profile and has proven itself in the treatment of chronic musculoskeletal pain. For chronic pain associated predominantly with neuropathy and central sensitization, the drugs of choice are tricyclic antidepressants, serotonin and norepinephrine reuptake inhibitor duloxetine, the α2δ ligands pregabalin and gabapentin. |
| format | Article |
| id | doaj-art-9f490d99819e4a75a422a2b991ea0ab4 |
| institution | Kabale University |
| issn | 1996-7012 2310-158X |
| language | Russian |
| publishDate | 2022-06-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj-art-9f490d99819e4a75a422a2b991ea0ab42025-08-20T03:59:54ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2022-06-011639610210.14412/1996-7012-2022-3-96-1022488Chronic musculoskeletal pain. Leading symptom or comorbid pathology?Yu. A. Olyunin0V.A. Nasonova Research Institute of RheumatologyCurrent trends in the development of personalized medicine dictate the need to interpret chronic pain as a multifactorial biopsychosocial phenomenon. A comprehensive integrated approach to the management of patients with chronic pain includes nosological diagnostics, assessment of factors that determine the persistence of pain and comorbid pathology, and the use of necessary pharmacological and non-pharmacological methods of treatment. Currently, primarily non-steroidal anti-inflammatory drugs are used for the pharmacotherapy of chronic pain, which is predominantly nociceptive in nature. Meloxicam (Movalis®), along with high efficacy, has a favorable safety profile and has proven itself in the treatment of chronic musculoskeletal pain. For chronic pain associated predominantly with neuropathy and central sensitization, the drugs of choice are tricyclic antidepressants, serotonin and norepinephrine reuptake inhibitor duloxetine, the α2δ ligands pregabalin and gabapentin.https://mrj.ima-press.net/mrj/article/view/1305rheumatic diseaseschronic paincentral sensitizationnociceptive paintreatment |
| spellingShingle | Yu. A. Olyunin Chronic musculoskeletal pain. Leading symptom or comorbid pathology? Современная ревматология rheumatic diseases chronic pain central sensitization nociceptive pain treatment |
| title | Chronic musculoskeletal pain. Leading symptom or comorbid pathology? |
| title_full | Chronic musculoskeletal pain. Leading symptom or comorbid pathology? |
| title_fullStr | Chronic musculoskeletal pain. Leading symptom or comorbid pathology? |
| title_full_unstemmed | Chronic musculoskeletal pain. Leading symptom or comorbid pathology? |
| title_short | Chronic musculoskeletal pain. Leading symptom or comorbid pathology? |
| title_sort | chronic musculoskeletal pain leading symptom or comorbid pathology |
| topic | rheumatic diseases chronic pain central sensitization nociceptive pain treatment |
| url | https://mrj.ima-press.net/mrj/article/view/1305 |
| work_keys_str_mv | AT yuaolyunin chronicmusculoskeletalpainleadingsymptomorcomorbidpathology |