Update on the Serum Biomarkers and Genetic Factors Associated with Safety and Efficacy of rt-PA Treatment in Acute Stroke Patients
An accurate understanding of the mechanisms underlying an individual's response to rt-PA treatment is critical to improve stroke patients' management. We thus reviewed the literature in order to identify biochemical and genetic factors that have been associated with safety and efficacy of...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Stroke Research and Treatment |
| Online Access: | http://dx.doi.org/10.4061/2011/182783 |
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| _version_ | 1849398816274382848 |
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| author | C. Nafría I. Fernández-Cadenas M. Mendioroz S. Domingues-Montanari M. Hernández-Guillamón J. Fernández-Morales A. del Río-Espínola D. Giralt L. Deu P. Delgado A. Rosell J. Montaner |
| author_facet | C. Nafría I. Fernández-Cadenas M. Mendioroz S. Domingues-Montanari M. Hernández-Guillamón J. Fernández-Morales A. del Río-Espínola D. Giralt L. Deu P. Delgado A. Rosell J. Montaner |
| author_sort | C. Nafría |
| collection | DOAJ |
| description | An accurate understanding of the mechanisms underlying an individual's response to rt-PA treatment is critical to improve stroke patients' management. We thus reviewed the literature in order to identify biochemical and genetic factors that have been associated with safety and efficacy of rt-PA administration after stroke. |
| format | Article |
| id | doaj-art-9f3f1a6a3d814069a00e21a47ef7aa49 |
| institution | Kabale University |
| issn | 2042-0056 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stroke Research and Treatment |
| spelling | doaj-art-9f3f1a6a3d814069a00e21a47ef7aa492025-08-20T03:38:30ZengWileyStroke Research and Treatment2042-00562011-01-01201110.4061/2011/182783182783Update on the Serum Biomarkers and Genetic Factors Associated with Safety and Efficacy of rt-PA Treatment in Acute Stroke PatientsC. Nafría0I. Fernández-Cadenas1M. Mendioroz2S. Domingues-Montanari3M. Hernández-Guillamón4J. Fernández-Morales5A. del Río-Espínola6D. Giralt7L. Deu8P. Delgado9A. Rosell10J. Montaner11Neurovascular Research Laboratory, Neurology and Medicine Departments, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), 08035 Barcelona, SpainNeurovascular Research Laboratory, Neurology and Medicine Departments, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), 08035 Barcelona, SpainNeurovascular Research Laboratory, Neurology and Medicine Departments, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), 08035 Barcelona, SpainNeurovascular Research Laboratory, Neurology and Medicine Departments, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), 08035 Barcelona, SpainNeurovascular Research Laboratory, Neurology and Medicine Departments, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), 08035 Barcelona, SpainNeurovascular Research Laboratory, Neurology and Medicine Departments, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), 08035 Barcelona, SpainNeurovascular Research Laboratory, Neurology and Medicine Departments, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), 08035 Barcelona, SpainNeurovascular Research Laboratory, Neurology and Medicine Departments, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), 08035 Barcelona, SpainNeurovascular Research Laboratory, Neurology and Medicine Departments, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), 08035 Barcelona, SpainNeurovascular Research Laboratory, Neurology and Medicine Departments, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), 08035 Barcelona, SpainNeurovascular Research Laboratory, Neurology and Medicine Departments, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), 08035 Barcelona, SpainNeurovascular Research Laboratory, Neurology and Medicine Departments, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), 08035 Barcelona, SpainAn accurate understanding of the mechanisms underlying an individual's response to rt-PA treatment is critical to improve stroke patients' management. We thus reviewed the literature in order to identify biochemical and genetic factors that have been associated with safety and efficacy of rt-PA administration after stroke.http://dx.doi.org/10.4061/2011/182783 |
| spellingShingle | C. Nafría I. Fernández-Cadenas M. Mendioroz S. Domingues-Montanari M. Hernández-Guillamón J. Fernández-Morales A. del Río-Espínola D. Giralt L. Deu P. Delgado A. Rosell J. Montaner Update on the Serum Biomarkers and Genetic Factors Associated with Safety and Efficacy of rt-PA Treatment in Acute Stroke Patients Stroke Research and Treatment |
| title | Update on the Serum Biomarkers and Genetic Factors Associated with Safety and Efficacy of rt-PA Treatment in Acute Stroke Patients |
| title_full | Update on the Serum Biomarkers and Genetic Factors Associated with Safety and Efficacy of rt-PA Treatment in Acute Stroke Patients |
| title_fullStr | Update on the Serum Biomarkers and Genetic Factors Associated with Safety and Efficacy of rt-PA Treatment in Acute Stroke Patients |
| title_full_unstemmed | Update on the Serum Biomarkers and Genetic Factors Associated with Safety and Efficacy of rt-PA Treatment in Acute Stroke Patients |
| title_short | Update on the Serum Biomarkers and Genetic Factors Associated with Safety and Efficacy of rt-PA Treatment in Acute Stroke Patients |
| title_sort | update on the serum biomarkers and genetic factors associated with safety and efficacy of rt pa treatment in acute stroke patients |
| url | http://dx.doi.org/10.4061/2011/182783 |
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