Atrial dysfunction: a contrast-free marker for HFpEF in obese diabetics—insights from comprehensive CMR and serum biomarker analyses

Atrial dysfunction: a contrast-free marker for HFpEF in obese diabetics—insights from comprehensive CMR and serum biomarker analyses

Abstract Background The diagnostic criteria for HFpEF remain inconsistently defined, further confounded by comorbidities such as obesity and type 2 diabetes mellitus (T2DM), which are thought to contribute to its pathogenesis via chronic pro-inflammatory mechanisms. This study aimed to evaluate the...

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Main Authors: Rebecca Elisabeth Beyer, Maximilian Leo Müller, Patrick Doeblin, Stefanie Maria Werhahn, Amedeo Chiribiri, Carsten Tschöpe, Smita Sampath, G. Brandon Atkins, Dawn Cislak, An Bautmans, John Palcza, Tom McAvoy, Asad Abu Bakar, Anita Y. H. Lee, Xuemei Zhao, Maximilian G. Posch, Johannes Wieditz, Radu Tanacli, Victoria Zieschang, Mithal Nassar, Seyedeh Mahsa Zamani, Christian Stehning, Frank Edelmann, Djawid Hashemi, Sebastian Kelle
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cardiovascular Diabetology
Subjects:
HFpEF
Obesity
Type 2 diabetes mellitus
Cardiac magnetic resonance
Left atrial strain
IL1RL1
Online Access:https://doi.org/10.1186/s12933-025-02808-3
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