Impact of COVID-19 pandemic on tuberculosis
Background: Tuberculosis (TB) is a disease of the respiratory system that spreads when a patient coughs, sneezes, or spits. COVID-19, another respiratory disease, created havoc in 2020 and 2021. During this pandemic, the whole healthcare system was diverted into COVID-19 patient care. It is importa...
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| Format: | Article |
| Language: | English |
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Golestan University of Medical Sciences
2025-01-01
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| Series: | Medical Laboratory Journal |
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| Online Access: | http://mlj.goums.ac.ir/article-1-1843-en.pdf |
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| author | Sae Pol Pooja Shah Vaishali Gaikwad Sujata Dharmshale Mansi Rajmane Rajesh Karyakarte |
| author_facet | Sae Pol Pooja Shah Vaishali Gaikwad Sujata Dharmshale Mansi Rajmane Rajesh Karyakarte |
| author_sort | Sae Pol |
| collection | DOAJ |
| description | Background: Tuberculosis (TB) is a disease of the respiratory system that spreads when a patient coughs, sneezes, or spits. COVID-19, another respiratory disease, created havoc in 2020 and 2021. During this pandemic, the whole healthcare system was diverted into COVID-19 patient care. It is important to determine what the status of TB was during the COVID-19 period. This study was mainly undertaken to detect the occurrence of Mycobacterium tuberculosis (M. tuberculosis) and rifampicin resistance before, during, and after COVID-19 restrictions were fully released.
Methods: Pulmonary and extrapulmonary samples from 1st January 2018 till 31st December 2022 were included in the present retrospective study. The period was divided as- 2018, 2019 - Before COVID-19 2020, 2021 -COVID-19 period with restrictions (Such as use of masks, social distancing, avoiding gatherings) 2022 -COVID-19 period without restrictions. All samples received in TB section were subjected to Cartridge-Based Nucleic Acid Amplification Test (CBNAAT). The samples were processed according to the manufacturer’s guidelines.
Results: There was no significant difference in samples received per year from 2018 to 2022. The positivity of M. tuberculosis decreased from 22.52% in the pre-COVID-19 period to 15.70% in the COVID-19 period with restrictions and increased again in 2022 (16.80%). Rifampicin resistance decreased from 10.40% to 6.89% in the COVID-19 period with restrictions. A decrease in positivity was not observed in extrapulmonary TB cases.
Conclusion: In the present study, total samples for TB received over five years were relatively the same. Restrictions imposed during the COVID-19 period could decrease TB and rifampicin resistance. Thus, imposing restrictions on TB-suspected and positive patients regularly can help prevent the spread of the disease. |
| format | Article |
| id | doaj-art-9f3015e5bc7c4c9a88461b8d93c21e86 |
| institution | Kabale University |
| issn | 2538-4449 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | Medical Laboratory Journal |
| spelling | doaj-art-9f3015e5bc7c4c9a88461b8d93c21e862025-08-20T03:27:48ZengGolestan University of Medical SciencesMedical Laboratory Journal2538-44492025-01-011911921Impact of COVID-19 pandemic on tuberculosisSae Pol0Pooja Shah1Vaishali Gaikwad2Sujata Dharmshale3Mansi Rajmane4Rajesh Karyakarte5 Department of Microbiology, BJ Medical College, Pune, India Department of Microbiology, BJ Medical College, Pune, India Department of Microbiology, Government Medical College, Satara, India Department of Microbiology, Government Medical College, Baramati, India Department of Microbiology, BJ Medical College, Pune, India Department of Microbiology, BJ Medical College, Pune, India Background: Tuberculosis (TB) is a disease of the respiratory system that spreads when a patient coughs, sneezes, or spits. COVID-19, another respiratory disease, created havoc in 2020 and 2021. During this pandemic, the whole healthcare system was diverted into COVID-19 patient care. It is important to determine what the status of TB was during the COVID-19 period. This study was mainly undertaken to detect the occurrence of Mycobacterium tuberculosis (M. tuberculosis) and rifampicin resistance before, during, and after COVID-19 restrictions were fully released. Methods: Pulmonary and extrapulmonary samples from 1st January 2018 till 31st December 2022 were included in the present retrospective study. The period was divided as- 2018, 2019 - Before COVID-19 2020, 2021 -COVID-19 period with restrictions (Such as use of masks, social distancing, avoiding gatherings) 2022 -COVID-19 period without restrictions. All samples received in TB section were subjected to Cartridge-Based Nucleic Acid Amplification Test (CBNAAT). The samples were processed according to the manufacturer’s guidelines. Results: There was no significant difference in samples received per year from 2018 to 2022. The positivity of M. tuberculosis decreased from 22.52% in the pre-COVID-19 period to 15.70% in the COVID-19 period with restrictions and increased again in 2022 (16.80%). Rifampicin resistance decreased from 10.40% to 6.89% in the COVID-19 period with restrictions. A decrease in positivity was not observed in extrapulmonary TB cases. Conclusion: In the present study, total samples for TB received over five years were relatively the same. Restrictions imposed during the COVID-19 period could decrease TB and rifampicin resistance. Thus, imposing restrictions on TB-suspected and positive patients regularly can help prevent the spread of the disease.http://mlj.goums.ac.ir/article-1-1843-en.pdfcovid-19mycobacterium tuberculosisrifampicin |
| spellingShingle | Sae Pol Pooja Shah Vaishali Gaikwad Sujata Dharmshale Mansi Rajmane Rajesh Karyakarte Impact of COVID-19 pandemic on tuberculosis Medical Laboratory Journal covid-19 mycobacterium tuberculosis rifampicin |
| title | Impact of COVID-19 pandemic on tuberculosis |
| title_full | Impact of COVID-19 pandemic on tuberculosis |
| title_fullStr | Impact of COVID-19 pandemic on tuberculosis |
| title_full_unstemmed | Impact of COVID-19 pandemic on tuberculosis |
| title_short | Impact of COVID-19 pandemic on tuberculosis |
| title_sort | impact of covid 19 pandemic on tuberculosis |
| topic | covid-19 mycobacterium tuberculosis rifampicin |
| url | http://mlj.goums.ac.ir/article-1-1843-en.pdf |
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