Microbiota, not host origin drives ex vivo intestinal epithelial responses

Microbiota, not host origin drives ex vivo intestinal epithelial responses

Microbial dysbiosis is an established finding in patients with inflammatory bowel disease (IBD), but host-microbial interactions are poorly understood. We aimed to unravel the effect of microbiota exposure on intestinal epithelial cells. Confluent Transwell® organoid monolayers of eight UC patients...

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Bibliographic Details
Main Authors: Kaline Arnauts, Padhmanand Sudhakar, Sare Verstockt, Cynthia Lapierre, Selina Potche, Clara Caenepeel, Bram Verstockt, Jeroen Raes, Séverine Vermeire, João Sabino, Catherine Verfaillie, Marc Ferrante
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Gut Microbes
Subjects:
Ulcerative colitis
epithelial cells
microbiota
dysbiosis
organoids
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2022.2089003
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