Intraosseous angioleiomyoma of the mandible- Report of a rare case
Leiomyoma (LM) is a smooth muscle tumor of a benign nature frequent in the genital tract of females. It is infrequent in the oral cavity. Oral LMs are generally of the angioleiomyoma (ALM) type. In this article, we present a rare case of oral ALM in a 24-year-old male who had a painless swelling in...
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Elsevier
2024-06-01
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| Series: | Oral Oncology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906024001754 |
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| author | K.S. Gamal Abdul Nasser S.G. Wasim Ahamed Madhu Narayan |
| author_facet | K.S. Gamal Abdul Nasser S.G. Wasim Ahamed Madhu Narayan |
| author_sort | K.S. Gamal Abdul Nasser |
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| description | Leiomyoma (LM) is a smooth muscle tumor of a benign nature frequent in the genital tract of females. It is infrequent in the oral cavity. Oral LMs are generally of the angioleiomyoma (ALM) type. In this article, we present a rare case of oral ALM in a 24-year-old male who had a painless swelling in the mandibular left buccal vestibule. Radiographically, there was the presence of left buccal cortical expansion. A tentative diagnosis of traumatic bone cyst/aneurysmal bone cyst was given. The microscopy of incisional biopsy revealed loose fibrovascular stroma and wavy spindle-shaped cells suggestive of a spindle cell neoplasm with features of neurofibroma. On immunohistochemical analysis, it was S100 negative but smooth muscle actin positive which led to the histopathological diagnosis of “LM.” The microscopic picture of the excised specimen showed spindle cells in an amorphous eosinophilic stroma, spicules of vital bone, dilated capillaries, and extravasated red blood cells. A final diagnosis of “ALM” was made. A local surgical excision was done. The follow-up of the patient was uneventful and there has been no recurrence to date. The intraosseous variety of LM, though a remote possibility, must be considered a differential diagnosis for central lesions of the mandible. |
| format | Article |
| id | doaj-art-9f22b3d015da4622a72eeb1def1449a2 |
| institution | Kabale University |
| issn | 2772-9060 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral Oncology Reports |
| spelling | doaj-art-9f22b3d015da4622a72eeb1def1449a22025-01-09T06:15:50ZengElsevierOral Oncology Reports2772-90602024-06-0110100329Intraosseous angioleiomyoma of the mandible- Report of a rare caseK.S. Gamal Abdul Nasser0S.G. Wasim Ahamed1Madhu Narayan2Dr. Nasser Dental Care, No 8, 13, Ritherdon Rd, Vepery, Purasaiwakkam, Chennai, Tamil Nadu, 600007, IndiaDr. Nasser Dental Care, No 8, 13, Ritherdon Rd, Vepery, Purasaiwakkam, Chennai, Tamil Nadu, 600007, IndiaCorresponding author. Department of Oral and Maxillofacial Pathology and Microbiology, S.R.M Dental College, Ramapuram, Bharathi Salai, Chennai, 600 089, India.; Department of Oral and Maxillofacial Pathology and Microbiology, S.R.M Dental College, Ramapuram, Bharathi Salai, Chennai, 600 089, IndiaLeiomyoma (LM) is a smooth muscle tumor of a benign nature frequent in the genital tract of females. It is infrequent in the oral cavity. Oral LMs are generally of the angioleiomyoma (ALM) type. In this article, we present a rare case of oral ALM in a 24-year-old male who had a painless swelling in the mandibular left buccal vestibule. Radiographically, there was the presence of left buccal cortical expansion. A tentative diagnosis of traumatic bone cyst/aneurysmal bone cyst was given. The microscopy of incisional biopsy revealed loose fibrovascular stroma and wavy spindle-shaped cells suggestive of a spindle cell neoplasm with features of neurofibroma. On immunohistochemical analysis, it was S100 negative but smooth muscle actin positive which led to the histopathological diagnosis of “LM.” The microscopic picture of the excised specimen showed spindle cells in an amorphous eosinophilic stroma, spicules of vital bone, dilated capillaries, and extravasated red blood cells. A final diagnosis of “ALM” was made. A local surgical excision was done. The follow-up of the patient was uneventful and there has been no recurrence to date. The intraosseous variety of LM, though a remote possibility, must be considered a differential diagnosis for central lesions of the mandible.http://www.sciencedirect.com/science/article/pii/S2772906024001754AngioleiomyomaImmunohistochemistryMandible |
| spellingShingle | K.S. Gamal Abdul Nasser S.G. Wasim Ahamed Madhu Narayan Intraosseous angioleiomyoma of the mandible- Report of a rare case Oral Oncology Reports Angioleiomyoma Immunohistochemistry Mandible |
| title | Intraosseous angioleiomyoma of the mandible- Report of a rare case |
| title_full | Intraosseous angioleiomyoma of the mandible- Report of a rare case |
| title_fullStr | Intraosseous angioleiomyoma of the mandible- Report of a rare case |
| title_full_unstemmed | Intraosseous angioleiomyoma of the mandible- Report of a rare case |
| title_short | Intraosseous angioleiomyoma of the mandible- Report of a rare case |
| title_sort | intraosseous angioleiomyoma of the mandible report of a rare case |
| topic | Angioleiomyoma Immunohistochemistry Mandible |
| url | http://www.sciencedirect.com/science/article/pii/S2772906024001754 |
| work_keys_str_mv | AT ksgamalabdulnasser intraosseousangioleiomyomaofthemandiblereportofararecase AT sgwasimahamed intraosseousangioleiomyomaofthemandiblereportofararecase AT madhunarayan intraosseousangioleiomyomaofthemandiblereportofararecase |