Antioxidative Stress Mechanisms behind Resveratrol: A Multidimensional Analysis
Over the past decade, oxidative stress was shown to be a key factor for various diseases. The term “antioxidant” also rapidly gained attention worldwide, viewed as beneficial in disease prevention. Resveratrol (RSV), a natural polyphenol, is a plant antitoxin formed in response to harmful environmen...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Journal of Food Quality |
| Online Access: | http://dx.doi.org/10.1155/2021/5571733 |
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| _version_ | 1849398809920012288 |
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| author | Tongyu Gu Nianmin Wang Tong Wu Qi Ge Liang Chen |
| author_facet | Tongyu Gu Nianmin Wang Tong Wu Qi Ge Liang Chen |
| author_sort | Tongyu Gu |
| collection | DOAJ |
| description | Over the past decade, oxidative stress was shown to be a key factor for various diseases. The term “antioxidant” also rapidly gained attention worldwide, viewed as beneficial in disease prevention. Resveratrol (RSV), a natural polyphenol, is a plant antitoxin formed in response to harmful environmental factors such as infection and injury. This antitoxin is found in grapes, strawberries, peanuts, or herbal medicines and exhibits many pharmacological effects involved in antitumor, anti-inflammatory, antiaging, and antioxidation stress mechanisms. Recently, numerous in vitro and in vivo experiments have shown that RSV harbors antioxidative stress properties and can be used as an antioxidant. Here, we review the free radical scavenging ability, antioxidant properties, signaling pathways, expression and regulation of antioxidant enzymes, and oxidative stress-related diseases associated with RSV. |
| format | Article |
| id | doaj-art-9f1fc903f1bc460ba8a6d39f0f54a2f0 |
| institution | Kabale University |
| issn | 0146-9428 1745-4557 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Food Quality |
| spelling | doaj-art-9f1fc903f1bc460ba8a6d39f0f54a2f02025-08-20T03:38:30ZengWileyJournal of Food Quality0146-94281745-45572021-01-01202110.1155/2021/55717335571733Antioxidative Stress Mechanisms behind Resveratrol: A Multidimensional AnalysisTongyu Gu0Nianmin Wang1Tong Wu2Qi Ge3Liang Chen4School of Life Sciences, Jiangsu University, Zhenjiang 212013, Jiangsu, ChinaSchool of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, Jiangsu, ChinaSchool of Life Sciences, Jiangsu University, Zhenjiang 212013, Jiangsu, ChinaSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, Jiangsu, ChinaSchool of Life Sciences, Jiangsu University, Zhenjiang 212013, Jiangsu, ChinaOver the past decade, oxidative stress was shown to be a key factor for various diseases. The term “antioxidant” also rapidly gained attention worldwide, viewed as beneficial in disease prevention. Resveratrol (RSV), a natural polyphenol, is a plant antitoxin formed in response to harmful environmental factors such as infection and injury. This antitoxin is found in grapes, strawberries, peanuts, or herbal medicines and exhibits many pharmacological effects involved in antitumor, anti-inflammatory, antiaging, and antioxidation stress mechanisms. Recently, numerous in vitro and in vivo experiments have shown that RSV harbors antioxidative stress properties and can be used as an antioxidant. Here, we review the free radical scavenging ability, antioxidant properties, signaling pathways, expression and regulation of antioxidant enzymes, and oxidative stress-related diseases associated with RSV.http://dx.doi.org/10.1155/2021/5571733 |
| spellingShingle | Tongyu Gu Nianmin Wang Tong Wu Qi Ge Liang Chen Antioxidative Stress Mechanisms behind Resveratrol: A Multidimensional Analysis Journal of Food Quality |
| title | Antioxidative Stress Mechanisms behind Resveratrol: A Multidimensional Analysis |
| title_full | Antioxidative Stress Mechanisms behind Resveratrol: A Multidimensional Analysis |
| title_fullStr | Antioxidative Stress Mechanisms behind Resveratrol: A Multidimensional Analysis |
| title_full_unstemmed | Antioxidative Stress Mechanisms behind Resveratrol: A Multidimensional Analysis |
| title_short | Antioxidative Stress Mechanisms behind Resveratrol: A Multidimensional Analysis |
| title_sort | antioxidative stress mechanisms behind resveratrol a multidimensional analysis |
| url | http://dx.doi.org/10.1155/2021/5571733 |
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