Ginseng polysaccharides circumvent acquired resistance to anti-PD-1 immunotherapy in patients with non-small cell lung cancer

Ginseng polysaccharides circumvent acquired resistance to anti-PD-1 immunotherapy in patients with non-small cell lung cancer

Saved in:

Bibliographic Details
Main Authors:	Jumin Huang, Ziming Wang, Feng Li, Huiting Wang, Yang Xiang, Runze Li, Chun Xie, Yuwei Wang, Zhihong Jiang, Yabing Cao, Wenhua Liang, Elaine Lai-Han Leung
Format:	Article
Language:	English
Published:	Elsevier 2025-02-01
Series:	Pharmacological Research
Subjects:	Immune checkpoint inhibitors Acquired resistance Non-small cell lung cancer Ginseng polysaccharides
Online Access:	http://www.sciencedirect.com/science/article/pii/S1043661825000362
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Enhancing the texture of fat-free yogurt with Panax ginseng leaf-stem extract and casein: Focusing on their softening effect
by: Dong Hyun Keum, et al.
Published: (2025-02-01)

Based on network pharmacology and molecular docking to study the mechanisms of active ingredients of ginseng in the treatment of atopic dermatitis
by: BU Jialiang, et al.
Published: (2025-01-01)

Ginseng-derived Nanoparticles Inhibit Lung Cancer Cell Growth by Promoting Macrophage M1 Polarization
by: Liangliang FAN, et al.
Published: (2025-02-01)

The occupational roles of hospitalized people due to Acquired Immune Deficiency Syndrome
by: Natália Augusto Nunes Gil, et al.
Published: (2014-04-01)

Structure, Immune and Anti-aging Activities of Capsular Polysaccharide Produced by Lactobacillus plantarum W1
by: Yongjiao GAO, et al.
Published: (2025-02-01)

Potential diagnostic tools for intensive care unit acquired weakness: A systematic review
by: Chen Xin, et al.
Published: (2025-06-01)

Characterization and Pickering emulsifying ability of Adinandra nitida leaf polysaccharides
by: Yingxuan Zhou, et al.
Published: (2025-01-01)

Ultrasonic/compound enzyme extraction, comparative characterisation and biological activity of Lonicera macranthoides polysaccharides
by: Mengdie Ren, et al.
Published: (2025-03-01)

Incidence of Rod Shaped Gramnegative Hospital Acquired Bacterial Infection and Antibiotic Resistance: A Retrospective Based Population Study
by: Kamal Jalal Rashid
Published: (2020-12-01)

Structural Characterization and Antioxidant Activity in Vivo of Polysaccharides from the Leaves of Hippophae rhamnoides L.
by: Niannian SONG, et al.
Published: (2025-02-01)

Polysaccharides from sea buckthorn — Ultrasound-assisted enzymatic extraction, purification, structural characterization, and antioxidant activity analysis
by: Jing Wen, et al.
Published: (2025-02-01)

Optimization of Enzymatic Hydrolysis Process, Structural Characterization and Antioxidant Activity Analysis of Gastrodia elata Polysaccharide
by: Yunfei HU, et al.
Published: (2025-02-01)

Ultrasound-induced modifications of Auricularia auricula polysaccharides: Implications for antioxidant and glucose-lowering activities
by: Te Yu, et al.
Published: (2025-01-01)

Food packaging films from natural polysaccharides and protein hydrogels: A comprehensive review
by: Mou Zhao, et al.
Published: (2025-01-01)

Effects of White Quinoa Polysaccharide on Regulation of Glucolipid Metabolism in Type 2 Diabetic Mice
by: Yanqing ZANG, et al.
Published: (2025-02-01)

Structural characteristics, sugar metabolizing enzyme activity and biological activity of Ganoderma lucidum polysaccharides at different growth stages
by: Shengjian Ma, et al.
Published: (2025-02-01)

A systematic review of advances in preparation, structures, bioactivities, structural-property relationships, and applications of Polyporus umbellatus polysaccharides
by: Wei Gao, et al.
Published: (2025-01-01)

Asparagus officinalis polysaccharide-loaded liposomal gels alleviate skin inflammation via inhibiting the NF-κB/MAPK pathways
by: Rongrui Zhang, et al.
Published: (2025-02-01)

Prognostic value of the lactate dehydrogenase to albumin ratio in advanced non-small cell lung cancer patients treated with the first-line PD-1 checkpoint inhibitors combined with chemotherapy
by: Meifeng Luo, et al.
Published: (2025-02-01)

Alleviation of DSS-induced colitis by Meconopsis polysaccharides correlated with reduced PI3K/AKT signaling and gut microbiome diversity
by: Jun Dai, et al.
Published: (2025-02-01)

Glycan degradation in Polygonati Rhizoma: Effects of traditional ‘nine steaming and nine basking’ on low molecular weight Fructans and polysaccharides
by: Xingyu Mei, et al.
Published: (2025-01-01)

Dietary supplementation of Astragalus polysaccharide or its nanoparticles enhances testicular hemodynamics, echotexture, scrotal circumference, concentration of testosterone, estradiol, nitric oxide, and total antioxidant capacity, and semen quality in mature Ossimi rams
by: Eman Fayez, et al.
Published: (2025-02-01)

Editorial: Beyond PD-1: novel checkpoint receptors and ligands as targets for immunotherapy
by: Jesse Haramati, et al.
Published: (2025-02-01)

Policy brief: Optimising antimicrobial usage in paediatric inpatient hospital settings
by: J Cloete, et al.
Published: (2024-04-01)

“God’s Grandeur” by Gerard Manley Hopkins. A Poetic Path into the Depths of Contemplation
by: Marcin Godawa
Published: (2023-06-01)

The impact of PD-L1 polymorphisms on the efficacy of immune checkpoint inhibitors depends on the tumor proportion score: a retrospective study
by: Keiichiro Suminaga, et al.
Published: (2025-02-01)

Selection strategy for encapsulation of hydrophilic and hydrophobic ingredients with food-grade materials: A systematic review and analysis
by: Ruihan Huang, et al.
Published: (2025-01-01)

Mitochondria-targeted photothermal-chemodynamic therapy enhances checkpoint blockade immunotherapy on colon cancer
by: Benchao Zheng, et al.
Published: (2025-04-01)

VSIG4+ tumor-associated macrophages mediate neutrophil infiltration and impair antigen-specific immunity in aggressive cancers through epigenetic regulation of SPP1
by: Zongfu Pan, et al.
Published: (2025-02-01)

Mutation of isocitrate dehydrogenase indicates favorable outcomes in pan-cancer immune checkpoint blockade
by: Zhiyang Huang, et al.
Published: (2025-02-01)

Effects of perioperative treatment of resectable adenocarcinoma of esophagogastric junction by immunotherapy (Adebrelimab) combined with chemotherapy (XELOX): protocol for a single-center, open-labeled study (AEGIS trial, neoadjuvant immunochemotherapy)
by: Yingyi Li, et al.
Published: (2025-02-01)

Improving NGOs’ participation in implementing HIV preventive interventions: a case of adolescents with high-risk behaviors in Iran
by: Haniye Sadat Sajadi, et al.
Published: (2025-02-01)

Efficacy and Safety of Low-Dose Lenvatinib and Toripalimab in Patients With Recurrent Platinum-Resistant Ovarian Cancer: Study Protocol of a Multicenter, Open-Label, Single-Arm, Phase II Clinical Trial
by: Su H, et al.
Published: (2025-02-01)

Five-year Survey of Bacterial Culture Isolates and Their Antibiogram in Pediatric Patients of Rural Tertiary Care Hospital of Central Gujarat
by: Krutika R Tandon, et al.
Published: (2024-07-01)

Efficacy of high-dose steroids versus low-dose steroids in the treatment of immune checkpoint inhibitor-associated myocarditis: a case series and systematic review
by: Xiuyue Man, et al.
Published: (2025-02-01)

Resetting the Hsc70-mediated lysosomal degradation of PD-L1 via a supramolecular meso peptide for the restoration of acquired anti-tumor T cell immunity
by: Yujia Zhao, et al.
Published: (2025-02-01)

Anti-cancer immunotherapy-related cardiotoxicity: preventable and treatable
by: Wu Helena T., et al.
Published: (2025-01-01)

Harnessing the power of seaweed: unveiling the potential of marine algae in drug discovery
by: Leonel Pereira, et al.
Published: (2023-12-01)

Properties of new polycationic bacteriochlorin photosensitizers: cytotoxicity and interaction with biofilms
by: Irina Tiganova, et al.
Published: (2024-09-01)

Combination of potassium oxonate with anti-PD-1 for the treatment of colorectal cancer
by: Yuanyuan Wang, et al.
Published: (2025-02-01)