Role of metabolic characteristics in the co-occurrence of insomnia, Alzheimer’s disease, and Parkinson’s disease: a Mendelian randomization study

Role of metabolic characteristics in the co-occurrence of insomnia, Alzheimer’s disease, and Parkinson’s disease: a Mendelian randomization study

ObjectiveThere reportedly exists a significant comorbidity between insomnia and neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), indicative of a potential link to serum metabolic dysregulation.MethodTo elucidate shared pathophysiological mechanisms between i...

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Bibliographic Details
Main Authors: Chengyong Liu, Chi Wang, Jing Jiang, Yuyang Bo, Lixiu Nan, Ying Zhang, Kongxi Zhu, Xiaoqiu Wang, Xinxin Feng, Xiaoyang Lian, Shan Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
insomnia
neurodegenerative diseases
Alzheimer’s disease
Parkinson’s disease
Mendelian randomization
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1436171/full
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