Safety and efficacy of low-temperature RA-flush solution in patients with moderate-to-severe calcified lesions (LOTA-II): a randomized, double-blind, multicenter study

Abstract Rotational atherectomy (RA) is an effective, mature, and specific treatment for calcified lesions. However, the incidence of RA-related myocardial injury remains high and has not been adequately addressed. To assess the safety and efficacy of low-temperature RA-flush solution versus room-te...

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Bibliographic Details
Main Authors:	Wei You, Xiang-qi Wu, Zhi-ming Wu, Yi-fei Wang, Tong-tong Shen, Bi Tang, Tian Xu, Liang-hong Ying, De-feng Pan, Song Yang, De-lu Yin, Fei Ye
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-05-01
Series:	Scientific Reports
Subjects:	Rotational atherectomy Calcified lesion Low temperature Flush solution Myocardial injury
Online Access:	https://doi.org/10.1038/s41598-025-02799-x
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Safety and efficacy of low-temperature RA-flush solution in patients with moderate-to-severe calcified lesions (LOTA-II): a randomized, double-blind, multicenter study

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