Mitochondrial morphology in fertile and infertile men: image processing and morphometric analysis of the sperm midpiece

Mitochondrial morphology in fertile and infertile men: image processing and morphometric analysis of the sperm midpiece

IntroductionThe male factor is responsible for 50% of infertility cases. Numerous studies have explored the relationship between human sperm morphology assessed via optical and electron microscopy and reproductive outcomes. In the sperm midpiece, mitochondria are arranged in a helical shape, forming...

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Main Authors: María Fernanda Skowronek, Santiago Pietroroia, Gabriel de Cola, Mauricio Ramos, Diego Silvera, Gabriela Casanova, Federico Lecumberry, Adriana Cassina, Rossana Sapiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
human infertility
sperm midpiece
sperm mitochondria
fluorescent probes
electron microscopy
image processing
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1609081/full
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