Diabetes Myonecrosis: A Debilitating Complication in an Indigenous Young Woman With Long Standing Type 1 Diabetes Mellitus
A 24-year-old Indigenous Australian female with long-standing, poorly controlled type 1 diabetes mellitus (T1DM) presented with 3 months’ history of unilateral thigh swelling and pain. Her laboratory investigations showed evidence of a persistent inflammatory state with normal creatine kinase. Infec...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2024/8839798 |
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| author | Jinwen He Liyan Wang Thomas Robertson Swetha Rangaswamaiah Usman H. Malabu |
| author_facet | Jinwen He Liyan Wang Thomas Robertson Swetha Rangaswamaiah Usman H. Malabu |
| author_sort | Jinwen He |
| collection | DOAJ |
| description | A 24-year-old Indigenous Australian female with long-standing, poorly controlled type 1 diabetes mellitus (T1DM) presented with 3 months’ history of unilateral thigh swelling and pain. Her laboratory investigations showed evidence of a persistent inflammatory state with normal creatine kinase. Infectious and autoimmune investigations were negative. Imaging demonstrated evidence of muscular oedema and atrophy. Muscular pain and swelling have a broad list of differential diagnoses. This case highlights a rare but potentially debilitating complication of diabetes mellitus—diabetic myonecrosis with its challenges in reaching a definitive diagnosis due to non-specific symptomology and laboratory findings. However, it is an important differential of leg pain and swelling to consider, particularly in those with long-standing diabetes and pre-existing microvascular complications. Glycaemic control is paramount in preventing this potentially severe diabetic complication. |
| format | Article |
| id | doaj-art-9efe504ca6de4f5dbed2da4edcfb1c5d |
| institution | OA Journals |
| issn | 2090-651X |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-9efe504ca6de4f5dbed2da4edcfb1c5d2025-08-20T02:18:32ZengWileyCase Reports in Endocrinology2090-651X2024-01-01202410.1155/2024/8839798Diabetes Myonecrosis: A Debilitating Complication in an Indigenous Young Woman With Long Standing Type 1 Diabetes MellitusJinwen He0Liyan Wang1Thomas Robertson2Swetha Rangaswamaiah3Usman H. Malabu4Department of Diabetes and EndocrinologyDepartment of Diabetes and EndocrinologyDepartment of Anatomical PathologyDepartment of Diabetes and EndocrinologyDepartment of Diabetes and EndocrinologyA 24-year-old Indigenous Australian female with long-standing, poorly controlled type 1 diabetes mellitus (T1DM) presented with 3 months’ history of unilateral thigh swelling and pain. Her laboratory investigations showed evidence of a persistent inflammatory state with normal creatine kinase. Infectious and autoimmune investigations were negative. Imaging demonstrated evidence of muscular oedema and atrophy. Muscular pain and swelling have a broad list of differential diagnoses. This case highlights a rare but potentially debilitating complication of diabetes mellitus—diabetic myonecrosis with its challenges in reaching a definitive diagnosis due to non-specific symptomology and laboratory findings. However, it is an important differential of leg pain and swelling to consider, particularly in those with long-standing diabetes and pre-existing microvascular complications. Glycaemic control is paramount in preventing this potentially severe diabetic complication.http://dx.doi.org/10.1155/2024/8839798 |
| spellingShingle | Jinwen He Liyan Wang Thomas Robertson Swetha Rangaswamaiah Usman H. Malabu Diabetes Myonecrosis: A Debilitating Complication in an Indigenous Young Woman With Long Standing Type 1 Diabetes Mellitus Case Reports in Endocrinology |
| title | Diabetes Myonecrosis: A Debilitating Complication in an Indigenous Young Woman With Long Standing Type 1 Diabetes Mellitus |
| title_full | Diabetes Myonecrosis: A Debilitating Complication in an Indigenous Young Woman With Long Standing Type 1 Diabetes Mellitus |
| title_fullStr | Diabetes Myonecrosis: A Debilitating Complication in an Indigenous Young Woman With Long Standing Type 1 Diabetes Mellitus |
| title_full_unstemmed | Diabetes Myonecrosis: A Debilitating Complication in an Indigenous Young Woman With Long Standing Type 1 Diabetes Mellitus |
| title_short | Diabetes Myonecrosis: A Debilitating Complication in an Indigenous Young Woman With Long Standing Type 1 Diabetes Mellitus |
| title_sort | diabetes myonecrosis a debilitating complication in an indigenous young woman with long standing type 1 diabetes mellitus |
| url | http://dx.doi.org/10.1155/2024/8839798 |
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