Interactions between starvation, cold stress and water velocities on immunological and metabolic responses of large yellow croaker

Research shows that natural starvation during cold months may enhance the croaker's cold tolerance, yet the high mortality rates persist, indicating that factors like water velocity may also play a critical role. This study investigates how low temperature, starvation and water velocities affec...

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Main Authors: Chengzhang Huang, Huirong Lv, Xuming Huang, Xiaolong Yin, Zhangjie Chu, Jungyeol Park, Junwook Hur, Yang Gao, Weiye Li
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Aquaculture Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352513425001322
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author Chengzhang Huang
Huirong Lv
Xuming Huang
Xiaolong Yin
Zhangjie Chu
Jungyeol Park
Junwook Hur
Yang Gao
Weiye Li
author_facet Chengzhang Huang
Huirong Lv
Xuming Huang
Xiaolong Yin
Zhangjie Chu
Jungyeol Park
Junwook Hur
Yang Gao
Weiye Li
author_sort Chengzhang Huang
collection DOAJ
description Research shows that natural starvation during cold months may enhance the croaker's cold tolerance, yet the high mortality rates persist, indicating that factors like water velocity may also play a critical role. This study investigates how low temperature, starvation and water velocities affect the croaker's survival, focusing on antioxidant capacity, metabolic, transcriptomic and microbiota changes, aiming to improve management strategies for this economically important species in aquaculture. 400 large yellow croakers were divided into fed and starved groups to assess cold tolerance under gradually decreasing temperatures, and swimming endurance under increased water velocities up to 0.35 m/s. The fish were subsequently subjected to simulated overwintering in controlled flow conditions at different velocities to observe survival rates. Samples from the fish, including liver and intestines, were collected for antioxidant capacity, transcriptomic, metabolomic and microbiota analyses. Our results demonstrate that starvation enhances cold tolerance in large yellow croakers, but reduces swimming endurance significantly, suggesting a complex interplay between metabolic preservation and physical capability. Transcriptomic analyses revealed a significant shift towards fatty acid oxidation and down-regulation of steroid biosynthesis pathways, particularly under combined stress conditions. Moreover, the excessive up-regulation of lipid metabolism led to the accelerated production of ROS, resulting in oxidative stress in large yellow croaker. Both liver metabolomics and intestinal microbiota composition studies illustrated significant alterations in metabolic profiles. These findings provide insights into how environmental stressors impact the physiological and metabolic dynamics of the large yellow croaker, offering potential strategies for improving resilience and survival in aquaculture settings.
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spelling doaj-art-9ef64e6ae8e14174973dec2df242a7512025-08-20T03:11:03ZengElsevierAquaculture Reports2352-51342025-07-014210274610.1016/j.aqrep.2025.102746Interactions between starvation, cold stress and water velocities on immunological and metabolic responses of large yellow croakerChengzhang Huang0Huirong Lv1Xuming Huang2Xiaolong Yin3Zhangjie Chu4Jungyeol Park5Junwook Hur6Yang Gao7Weiye Li8Fishery School, Zhejiang Ocean University, Zhoushan 316022, ChinaDepartment of Aquaculture and Aquatic Science, Kunsan National University, Gunsan 54150, South KoreaFishery School, Zhejiang Ocean University, Zhoushan 316022, ChinaZhoushan Fisheries Research Institute, Zhoushan, ChinaFishery School, Zhejiang Ocean University, Zhoushan 316022, ChinaDepartment of Aquaculture and Aquatic Science, Kunsan National University, Gunsan 54150, South KoreaDepartment of Aquaculture and Aquatic Science, Kunsan National University, Gunsan 54150, South KoreaFishery School, Zhejiang Ocean University, Zhoushan 316022, China; Correspondence to: Fishery School, Zhejiang Ocean University, No. 1 Haida south road, Lincheng street, Dinghai district, Zhoushan, Zhejiang, China.Zhoushan Fisheries Research Institute, Zhoushan, China; Correspondence to: Fishery School, Zhejiang Ocean University, No. 1 Haida south road, Lincheng street, Dinghai district, Zhoushan, Zhejiang, China.Research shows that natural starvation during cold months may enhance the croaker's cold tolerance, yet the high mortality rates persist, indicating that factors like water velocity may also play a critical role. This study investigates how low temperature, starvation and water velocities affect the croaker's survival, focusing on antioxidant capacity, metabolic, transcriptomic and microbiota changes, aiming to improve management strategies for this economically important species in aquaculture. 400 large yellow croakers were divided into fed and starved groups to assess cold tolerance under gradually decreasing temperatures, and swimming endurance under increased water velocities up to 0.35 m/s. The fish were subsequently subjected to simulated overwintering in controlled flow conditions at different velocities to observe survival rates. Samples from the fish, including liver and intestines, were collected for antioxidant capacity, transcriptomic, metabolomic and microbiota analyses. Our results demonstrate that starvation enhances cold tolerance in large yellow croakers, but reduces swimming endurance significantly, suggesting a complex interplay between metabolic preservation and physical capability. Transcriptomic analyses revealed a significant shift towards fatty acid oxidation and down-regulation of steroid biosynthesis pathways, particularly under combined stress conditions. Moreover, the excessive up-regulation of lipid metabolism led to the accelerated production of ROS, resulting in oxidative stress in large yellow croaker. Both liver metabolomics and intestinal microbiota composition studies illustrated significant alterations in metabolic profiles. These findings provide insights into how environmental stressors impact the physiological and metabolic dynamics of the large yellow croaker, offering potential strategies for improving resilience and survival in aquaculture settings.http://www.sciencedirect.com/science/article/pii/S2352513425001322Larger yellow croakerStarvationColdWater velocityImmune response
spellingShingle Chengzhang Huang
Huirong Lv
Xuming Huang
Xiaolong Yin
Zhangjie Chu
Jungyeol Park
Junwook Hur
Yang Gao
Weiye Li
Interactions between starvation, cold stress and water velocities on immunological and metabolic responses of large yellow croaker
Aquaculture Reports
Larger yellow croaker
Starvation
Cold
Water velocity
Immune response
title Interactions between starvation, cold stress and water velocities on immunological and metabolic responses of large yellow croaker
title_full Interactions between starvation, cold stress and water velocities on immunological and metabolic responses of large yellow croaker
title_fullStr Interactions between starvation, cold stress and water velocities on immunological and metabolic responses of large yellow croaker
title_full_unstemmed Interactions between starvation, cold stress and water velocities on immunological and metabolic responses of large yellow croaker
title_short Interactions between starvation, cold stress and water velocities on immunological and metabolic responses of large yellow croaker
title_sort interactions between starvation cold stress and water velocities on immunological and metabolic responses of large yellow croaker
topic Larger yellow croaker
Starvation
Cold
Water velocity
Immune response
url http://www.sciencedirect.com/science/article/pii/S2352513425001322
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